| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the protriptyline-5438 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATP10A | ATPase, class V, type 10A |
| ATXN1 | ataxin 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP1 | bone morphogenetic protein 1 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CCDC132 | coiled-coil domain containing 132 |
| CCKAR | cholecystokinin A receptor |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| COL4A2 | collagen, type IV, alpha 2 |
| COL5A1 | collagen, type V, alpha 1 |
| COMP | cartilage oligomeric matrix protein |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPQ | carboxypeptidase Q |
| DCX | doublecortin |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DICER1 | dicer 1, ribonuclease type III |
| DMPK | dystrophia myotonica-protein kinase |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOCK5 | dedicator of cytokinesis 5 |
| DOPEY2 | dopey family member 2 |
| DUSP4 | dual specificity phosphatase 4 |
| ELN | elastin |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ETV1 | ets variant 1 |
| FAM105A | family with sequence similarity 105, member A |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FSTL1 | follistatin-like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLRX | glutaredoxin (thioltransferase) |
| GPR137 | G protein-coupled receptor 137 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXB6 | homeobox B6 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL11 | interleukin 11 |
| IL24 | interleukin 24 |
| INSIG1 | insulin induced gene 1 |
| IRF9 | interferon regulatory factor 9 |
| IRS2 | insulin receptor substrate 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KLF13 | Kruppel-like factor 13 |
| KRT20 | keratin 20, type I |
| LAMC2 | laminin, gamma 2 |
| LOC100131532 | uncharacterized LOC100131532 |
| LPIN1 | lipin 1 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTCL1 | microtubule crosslinking factor 1 |
| MTSS1L | metastasis suppressor 1-like |
| NEU3 | sialidase 3 (membrane sialidase) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NXPH4 | neurexophilin 4 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLIN2 | perilipin 2 |
| PLXNB1 | plexin B1 |
| POLM | polymerase (DNA directed), mu |
| POU6F1 | POU class 6 homeobox 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RHOQ | ras homolog family member Q |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| S100A1 | S100 calcium binding protein A1 |
| S100A2 | S100 calcium binding protein A2 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| TLR2 | toll-like receptor 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM212 | transmembrane protein 212 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| USP22 | ubiquitin specific peptidase 22 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADRA2C | adrenoceptor alpha 2C |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP13A2 | ATPase type 13A2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCNE1 | cyclin E1 |
| CFD | complement factor D (adipsin) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLGN | calmegin |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| COL4A5 | collagen, type IV, alpha 5 |
| CUL9 | cullin 9 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DUSP2 | dual specificity phosphatase 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM212B | family with sequence similarity 212, member B |
| FANCE | Fanconi anemia, complementation group E |
| FGGY | FGGY carbohydrate kinase domain containing |
| FGL1 | fibrinogen-like 1 |
| FLCN | folliculin |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GMPR | guanosine monophosphate reductase |
| GPATCH2L | G patch domain containing 2-like |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIRA | histone cell cycle regulator |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4A | histone cluster 1, H4a |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| IRF1 | interferon regulatory factor 1 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIAA0754 | KIAA0754 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC730101 | uncharacterized LOC730101 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| METTL2B | methyltransferase like 2B |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDE12 | phosphodiesterase 12 |
| PER3 | period circadian clock 3 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| RBL1 | retinoblastoma-like 1 |
| RNF31 | ring finger protein 31 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL10L | ribosomal protein L10-like |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCRIB | scribbled planar cell polarity protein |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SDC3 | syndecan 3 |
| SKI | SKI proto-oncogene |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNIP1 | Smad nuclear interacting protein 1 |
| TAGLN | transgelin |
| TAOK1 | TAO kinase 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBX19 | T-box 19 |
| TESC | tescalcin |
| TET3 | tet methylcytosine dioxygenase 3 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VASH2 | vasohibin 2 |
| VGF | VGF nerve growth factor inducible |
| WDR62 | WD repeat domain 62 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF219 | zinc finger protein 219 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
| ZNF767P | zinc finger family member 767, pseudogene |
