| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the protriptyline-6338 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATF6B | activating transcription factor 6 beta |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC71 | coiled-coil domain containing 71 |
| CCNG2 | cyclin G2 |
| CDC14B | cell division cycle 14B |
| CDC25C | cell division cycle 25C |
| CDK13 | cyclin-dependent kinase 13 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| COL1A1 | collagen, type I, alpha 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CTH | cystathionine gamma-lyase |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DST | dystonin |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EFNA3 | ephrin-A3 |
| EGFR | epidermal growth factor receptor |
| ELAC2 | elaC ribonuclease Z 2 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EMP1 | epithelial membrane protein 1 |
| FGL1 | fibrinogen-like 1 |
| FOXG1 | forkhead box G1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAS8 | growth arrest-specific 8 |
| GLP1R | glucagon-like peptide 1 receptor |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC10 | homeobox C10 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT122 | intraflagellar transport 122 |
| IL16 | interleukin 16 |
| IL1A | interleukin 1, alpha |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| INSIG1 | insulin induced gene 1 |
| KLK2 | kallikrein-related peptidase 2 |
| KYNU | kynureninase |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMTK1 | lemur tail kinase 1 |
| LOC81691 | exonuclease NEF-sp |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MEGF9 | multiple EGF-like-domains 9 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MYOF | myoferlin |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF1 | neurofibromin 1 |
| NNAT | neuronatin |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRXN3 | neurexin 3 |
| OLFML3 | olfactomedin-like 3 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PDGFRL | platelet-derived growth factor receptor-like |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PURA | purine-rich element binding protein A |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPS3A | ribosomal protein S3A |
| S100A1 | S100 calcium binding protein A1 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC22A17 | solute carrier family 22, member 17 |
| SMAD7 | SMAD family member 7 |
| SPRR1B | small proline-rich protein 1B |
| SQSTM1 | sequestosome 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAPBP | TAP binding protein (tapasin) |
| TBXA2R | thromboxane A2 receptor |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TSGA10 | testis specific, 10 |
| WDR1 | WD repeat domain 1 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CABIN1 | calcineurin binding protein 1 |
| CCDC106 | coiled-coil domain containing 106 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSD | cathepsin D |
| CTSF | cathepsin F |
| ECM1 | extracellular matrix protein 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EXOSC9 | exosome component 9 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FPGS | folylpolyglutamate synthase |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| FUZ | fuzzy planar cell polarity protein |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| HIRA | histone cell cycle regulator |
| HIST1H3G | histone cluster 1, H3g |
| HOXA4 | homeobox A4 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSPA2 | heat shock 70kDa protein 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGA10 | integrin, alpha 10 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF13B | kinesin family member 13B |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT75 | keratin 75, type II |
| LMBR1L | limb development membrane protein 1-like |
| LMNB2 | lamin B2 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCRS1 | microspherule protein 1 |
| MISP | mitotic spindle positioning |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MT1M | metallothionein 1M |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MUTYH | mutY homolog |
| MYBBP1A | MYB binding protein (P160) 1a |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PCBP4 | poly(rC) binding protein 4 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPCDC | phosphopantothenoylcysteine decarboxylase |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PRPH | peripherin |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RIN1 | Ras and Rab interactor 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETMAR | SET domain and mariner transposase fusion gene |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SMAD5 | SMAD family member 5 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNPO | synaptopodin |
| TAOK1 | TAO kinase 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TH | tyrosine hydroxylase |
| TMEM120B | transmembrane protein 120B |
| TMEM134 | transmembrane protein 134 |
| TMEM183A | transmembrane protein 183A |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM66 | tripartite motif containing 66 |
| TSPAN1 | tetraspanin 1 |
| TSPYL2 | TSPY-like 2 |
| TUBA3D | tubulin, alpha 3d |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| WDR91 | WD repeat domain 91 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| XYLT2 | xylosyltransferase II |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF671 | zinc finger protein 671 |
| ZNF696 | zinc finger protein 696 |
