| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the protriptyline-6498 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADCK4 | aarF domain containing kinase 4 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AK2 | adenylate kinase 2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APOC1 | apolipoprotein C-I |
| AQP3 | aquaporin 3 (Gill blood group) |
| ART1 | ADP-ribosyltransferase 1 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CAPN9 | calpain 9 |
| CCDC68 | coiled-coil domain containing 68 |
| CD101 | CD101 molecule |
| CD1A | CD1a molecule |
| CD5 | CD5 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| CPA4 | carboxypeptidase A4 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DENND5B | DENN/MADD domain containing 5B |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| FBN1 | fibrillin 1 |
| FER | fer (fps/fes related) tyrosine kinase |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GALR3 | galanin receptor 3 |
| GLUL | glutamate-ammonia ligase |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXB5 | homeobox B5 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INO80D | INO80 complex subunit D |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KIAA1024 | KIAA1024 |
| KLF13 | Kruppel-like factor 13 |
| KLHL29 | kelch-like family member 29 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LARGE | like-glycosyltransferase |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| LY9 | lymphocyte antigen 9 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MARS | methionyl-tRNA synthetase |
| MBD1 | methyl-CpG binding domain protein 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MOB3B | MOB kinase activator 3B |
| MVD | mevalonate (diphospho) decarboxylase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NUP88 | nucleoporin 88kDa |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PIDD1 | p53-induced death domain protein 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLA2G3 | phospholipase A2, group III |
| PLAUR | plasminogen activator, urokinase receptor |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PURG | purine-rich element binding protein G |
| RIN1 | Ras and Rab interactor 1 |
| RND1 | Rho family GTPase 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SHOX2 | short stature homeobox 2 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNCAIP | synuclein, alpha interacting protein |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SQLE | squalene epoxidase |
| STK11 | serine/threonine kinase 11 |
| STK17B | serine/threonine kinase 17b |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TFEB | transcription factor EB |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPP1 | tripeptidyl peptidase I |
| TRIM2 | tripartite motif containing 2 |
| TSPY1 | testis specific protein, Y-linked 1 |
| ULBP2 | UL16 binding protein 2 |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF318 | zinc finger protein 318 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTL8 | actin-like 8 |
| ACVR2B | activin A receptor, type IIB |
| ADCY6 | adenylate cyclase 6 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARL15 | ADP-ribosylation factor-like 15 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C5 | complement component 5 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC9 | coiled-coil domain containing 9 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD83 | CD83 molecule |
| CENPT | centromere protein T |
| CHKB | choline kinase beta |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLDN9 | claudin 9 |
| CORT | cortistatin |
| CST6 | cystatin E/M |
| CSTA | cystatin A (stefin A) |
| CXXC4 | CXXC finger protein 4 |
| DAPK3 | death-associated protein kinase 3 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| ECI1 | enoyl-CoA delta isomerase 1 |
| EMID1 | EMI domain containing 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM63A | family with sequence similarity 63, member A |
| FBXO46 | F-box protein 46 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXN2 | forkhead box N2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLUD2 | glutamate dehydrogenase 2 |
| GMIP | GEM interacting protein |
| GPR3 | G protein-coupled receptor 3 |
| GPX2 | glutathione peroxidase 2 |
| GSTT1 | glutathione S-transferase theta 1 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3B | histone cluster 1, H3b |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IL15RA | interleukin 15 receptor, alpha |
| JMJD4 | jumonji domain containing 4 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMTK1 | lemur tail kinase 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC20 | leucine rich repeat containing 20 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| METRN | meteorin, glial cell differentiation regulator |
| MITF | microphthalmia-associated transcription factor |
| MTSS1L | metastasis suppressor 1-like |
| MYO1E | myosin IE |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NLRX1 | NLR family member X1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| PDGFD | platelet derived growth factor D |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLAT | plasminogen activator, tissue |
| PRMT7 | protein arginine methyltransferase 7 |
| RAB36 | RAB36, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASA2 | RAS p21 protein activator 2 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDC3 | syndecan 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC41A3 | solute carrier family 41, member 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| STK16 | serine/threonine kinase 16 |
| TFF2 | trefoil factor 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRAIP | TRAF interacting protein |
| TSPAN2 | tetraspanin 2 |
| TSPYL2 | TSPY-like 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| VIM | vimentin |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF446 | zinc finger protein 446 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
