| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the proxymetacaine-5433 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI2 | abl-interactor 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AIF1 | allograft inflammatory factor 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ASPH | aspartate beta-hydroxylase |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP5 | bone morphogenetic protein 5 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CADM3 | cell adhesion molecule 3 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHI3L2 | chitinase 3-like 2 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLDN17 | claudin 17 |
| CNTNAP3B | contactin associated protein-like 3B |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DTNA | dystrobrevin, alpha |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| EPHA1 | EPH receptor A1 |
| EPHB2 | EPH receptor B2 |
| FBLN1 | fibulin 1 |
| FGF4 | fibroblast growth factor 4 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GLS | glutaminase |
| GM2A | GM2 ganglioside activator |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIC2 | hypermethylated in cancer 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFT27 | intraflagellar transport 27 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IL17RC | interleukin 17 receptor C |
| IL9R | interleukin 9 receptor |
| IQCC | IQ motif containing C |
| IRS2 | insulin receptor substrate 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMK1 | LIM domain kinase 1 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LPXN | leupaxin |
| MBD3 | methyl-CpG binding domain protein 3 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MSR1 | macrophage scavenger receptor 1 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NGDN | neuroguidin, EIF4E binding protein |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCDHB11 | protocadherin beta 11 |
| PCM1 | pericentriolar material 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRAMEF11 | PRAME family member 11 |
| PTCH2 | patched 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PXN | paxillin |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RAP1GAP | RAP1 GTPase activating protein |
| RGS20 | regulator of G-protein signaling 20 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SETD1B | SET domain containing 1B |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYT2 | synaptotagmin II |
| TAPBP | TAP binding protein (tapasin) |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| UBE3A | ubiquitin protein ligase E3A |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOD | apolipoprotein D |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBC3 | BCL2 binding component 3 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCNO | cyclin O |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CTSF | cathepsin F |
| DBF4B | DBF4 zinc finger B |
| DEAF1 | DEAF1 transcription factor |
| DMTN | dematin actin binding protein |
| DOCK1 | dedicator of cytokinesis 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| FAM212B | family with sequence similarity 212, member B |
| FBXO31 | F-box protein 31 |
| FBXO4 | F-box protein 4 |
| FER | fer (fps/fes related) tyrosine kinase |
| FLJ22184 | |
| FOSL1 | FOS-like antigen 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GAMT | guanidinoacetate N-methyltransferase |
| GPR27 | G protein-coupled receptor 27 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2AK | histone cluster 1, H2ak |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| ITGA10 | integrin, alpha 10 |
| KIAA0754 | KIAA0754 |
| KLF2 | Kruppel-like factor 2 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LEFTY1 | left-right determination factor 1 |
| LHX6 | LIM homeobox 6 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LRRC6 | leucine rich repeat containing 6 |
| LYRM9 | LYR motif containing 9 |
| MCOLN1 | mucolipin 1 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCDHA9 | protocadherin alpha 9 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PICK1 | protein interacting with PRKCA 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POLL | polymerase (DNA directed), lambda |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKCE | protein kinase C, epsilon |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB30 | RAB30, member RAS oncogene family |
| RIN1 | Ras and Rab interactor 1 |
| RLN1 | relaxin 1 |
| RNF123 | ring finger protein 123 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF170 | ring finger protein 170 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| S100A4 | S100 calcium binding protein A4 |
| SDC3 | syndecan 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SMA4 | glucuronidase, beta pseudogene |
| SMIM14 | small integral membrane protein 14 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPON2 | spondin 2, extracellular matrix protein |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STRA6 | stimulated by retinoic acid 6 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM104 | transmembrane protein 104 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM36 | tripartite motif containing 36 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
