| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the proxymetacaine-6332 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AFF2 | AF4/FMR2 family, member 2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASPN | asporin |
| ASTN2 | astrotactin 2 |
| B9D1 | B9 protein domain 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BAGE | B melanoma antigen |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C8A | complement component 8, alpha polypeptide |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CALD1 | caldesmon 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEP68 | centrosomal protein 68kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSNK1E | casein kinase 1, epsilon |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYTH1 | cytohesin 1 |
| CYTH3 | cytohesin 3 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EMP1 | epithelial membrane protein 1 |
| ERF | Ets2 repressor factor |
| FAM13A | family with sequence similarity 13, member A |
| FAM65B | family with sequence similarity 65, member B |
| FDPS | farnesyl diphosphate synthase |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FRZB | frizzled-related protein |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HOXC10 | homeobox C10 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNIP1 | Kv channel interacting protein 1 |
| KLF12 | Kruppel-like factor 12 |
| KRT86 | keratin 86, type II |
| LHX2 | LIM homeobox 2 |
| LIMD1 | LIM domains containing 1 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LMTK1 | lemur tail kinase 1 |
| LOC100131532 | uncharacterized LOC100131532 |
| LSP1 | lymphocyte-specific protein 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPT | microtubule-associated protein tau |
| MBD3 | methyl-CpG binding domain protein 3 |
| MDFI | MyoD family inhibitor |
| MON1B | MON1 secretory trafficking family member B |
| NCOR2 | nuclear receptor corepressor 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NOX1 | NADPH oxidase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PRAMEF12 | PRAME family member 12 |
| PRDX2 | peroxiredoxin 2 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB36 | RAB36, member RAS oncogene family |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF39 | ring finger protein 39 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFTPB | surfactant protein B |
| SLA | Src-like-adaptor |
| SNX13 | sorting nexin 13 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPTA1 | spectrin, alpha, erythrocytic 1 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STK24 | serine/threonine kinase 24 |
| TBC1D17 | TBC1 domain family, member 17 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRIM49 | tripartite motif containing 49 |
| UBXN1 | UBX domain protein 1 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| WDR1 | WD repeat domain 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BLMH | bleomycin hydrolase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5 | complement component 5 |
| CCDC47 | coiled-coil domain containing 47 |
| CCNJ | cyclin J |
| CENPQ | centromere protein Q |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHEK2 | checkpoint kinase 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CUL9 | cullin 9 |
| DENND4B | DENN/MADD domain containing 4B |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| DYSF | dysferlin |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| EXOSC9 | exosome component 9 |
| FAM131A | family with sequence similarity 131, member A |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR176 | G protein-coupled receptor 176 |
| GSR | glutathione reductase |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL11RA | interleukin 11 receptor, alpha |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF9 | interferon regulatory factor 9 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JMJD4 | jumonji domain containing 4 |
| KIAA0232 | KIAA0232 |
| KIAA0753 | KIAA0753 |
| KRT75 | keratin 75, type II |
| LMNB1 | lamin B1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NRSN2 | neurensin 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PDGFD | platelet derived growth factor D |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| POR | P450 (cytochrome) oxidoreductase |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RBM38 | RNA binding motif protein 38 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SALL2 | spalt-like transcription factor 2 |
| SCG5 | secretogranin V |
| SCPEP1 | serine carboxypeptidase 1 |
| SHROOM2 | shroom family member 2 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNPH | syntaphilin |
| SPATA2L | spermatogenesis associated 2-like |
| SPEG | SPEG complex locus |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNPO | synaptopodin |
| SYTL2 | synaptotagmin-like 2 |
| TAOK1 | TAO kinase 1 |
| TBK1 | TANK-binding kinase 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM134 | transmembrane protein 134 |
| TMEM8A | transmembrane protein 8A |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TTC4 | tetratricopeptide repeat domain 4 |
| UNC45A | unc-45 homolog A (C. elegans) |
| VPS4A | vacuolar protein sorting 4 homolog A (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF350 | zinc finger protein 350 |
| ZNF629 | zinc finger protein 629 |
| ZNF668 | zinc finger protein 668 |
