| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the proxymetacaine-6492 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGER | advanced glycosylation end product-specific receptor |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ARTN | artemin |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| BTG4 | B-cell translocation gene 4 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CALD1 | caldesmon 1 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC102B | coiled-coil domain containing 102B |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD6 | CD6 molecule |
| CEMP1 | cementum protein 1 |
| CFP | complement factor properdin |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COL10A1 | collagen, type X, alpha 1 |
| CTSS | cathepsin S |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAPK1 | death-associated protein kinase 1 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DCX | doublecortin |
| DOK4 | docking protein 4 |
| DTNA | dystrobrevin, alpha |
| DVL3 | dishevelled segment polarity protein 3 |
| EFNB3 | ephrin-B3 |
| EMX1 | empty spiracles homeobox 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EPHB2 | EPH receptor B2 |
| FAM129A | family with sequence similarity 129, member A |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAS1 | growth arrest-specific 1 |
| GLRA1 | glycine receptor, alpha 1 |
| GPR85 | G protein-coupled receptor 85 |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| HHAT | hedgehog acyltransferase |
| HOXD10 | homeobox D10 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL1RN | interleukin 1 receptor antagonist |
| IL7R | interleukin 7 receptor |
| IMPG1 | interphotoreceptor matrix proteoglycan 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KLHL29 | kelch-like family member 29 |
| KLHL35 | kelch-like family member 35 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LY9 | lymphocyte antigen 9 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MIR622 | microRNA 622 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MST1 | macrophage stimulating 1 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NOL10 | nucleolar protein 10 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OSBP2 | oxysterol binding protein 2 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PER1 | period circadian clock 1 |
| PLCL2 | phospholipase C-like 2 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PON1 | paraoxonase 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRG4 | proteoglycan 4 |
| PRND | prion protein 2 (dublet) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RBBP9 | retinoblastoma binding protein 9 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFPL1 | ret finger protein-like 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEC24D | SEC24 family member D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| STC1 | stanniocalcin 1 |
| STX7 | syntaxin 7 |
| TMEM246 | transmembrane protein 246 |
| TNNT2 | troponin T type 2 (cardiac) |
| TOP3B | topoisomerase (DNA) III beta |
| TRIM49 | tripartite motif containing 49 |
| TSSK2 | testis-specific serine kinase 2 |
| VARS | valyl-tRNA synthetase |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZNF507 | zinc finger protein 507 |
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ARSB | arylsulfatase B |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC69 | coiled-coil domain containing 69 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK20 | cyclin-dependent kinase 20 |
| CDON | cell adhesion associated, oncogene regulated |
| CEL | carboxyl ester lipase |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRBN | cereblon |
| CUL9 | cullin 9 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EPHA2 | EPH receptor A2 |
| FAM110B | family with sequence similarity 110, member B |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HCFC2 | host cell factor C2 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H4A | histone cluster 1, H4a |
| HOXA4 | homeobox A4 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFT22 | intraflagellar transport 22 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KIF16B | kinesin family member 16B |
| KLHL28 | kelch-like family member 28 |
| LOC730101 | uncharacterized LOC730101 |
| LPXN | leupaxin |
| LRRC61 | leucine rich repeat containing 61 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFAP2 | microfibrillar-associated protein 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MT1H | metallothionein 1H |
| MYO1E | myosin IE |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OLFML2A | olfactomedin-like 2A |
| OTUD3 | OTU deubiquitinase 3 |
| PCDHB8 | protocadherin beta 8 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PER3 | period circadian clock 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLD3 | phospholipase D family, member 3 |
| PRR7 | proline rich 7 (synaptic) |
| REEP4 | receptor accessory protein 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF122 | ring finger protein 122 |
| SH2D4A | SH2 domain containing 4A |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STK16 | serine/threonine kinase 16 |
| STON1 | stonin 1 |
| STXBP2 | syntaxin binding protein 2 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM62 | transmembrane protein 62 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSPAN2 | tetraspanin 2 |
| UPK3B | uroplakin 3B |
| USP18 | ubiquitin specific peptidase 18 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF165 | zinc finger protein 165 |
| ZNF365 | zinc finger protein 365 |
| ZNF862 | zinc finger protein 862 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
