| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the proxyphylline-5993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ANK2 | ankyrin 2, neuronal |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCKAR | cholecystokinin A receptor |
| CCNJL | cyclin J-like |
| CEP162 | centrosomal protein 162kDa |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CREBBP | CREB binding protein |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DSC2 | desmocollin 2 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EMID1 | EMI domain containing 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| ESR1 | estrogen receptor 1 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FAM212B | family with sequence similarity 212, member B |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GH1 | growth hormone 1 |
| GK2 | glycerol kinase 2 |
| GRB10 | growth factor receptor-bound protein 10 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HBEGF | heparin-binding EGF-like growth factor |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| ITM2C | integral membrane protein 2C |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIF1C | kinesin family member 1C |
| KLF13 | Kruppel-like factor 13 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| KRT17 | keratin 17, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LAT2 | linker for activation of T cells family, member 2 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBTD1 | mbt domain containing 1 |
| MINK1 | misshapen-like kinase 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH17 | protocadherin 17 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDGFD | platelet derived growth factor D |
| PIP | prolactin-induced protein |
| POPDC3 | popeye domain containing 3 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| RASSF9 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 |
| RPGRIP1L | RPGRIP1-like |
| RPH3A | rabphilin 3A |
| RUNX1 | runt-related transcription factor 1 |
| SATB2 | SATB homeobox 2 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SFTPD | surfactant protein D |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SRCAP | Snf2-related CREBBP activator protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TADA2A | transcriptional adaptor 2A |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TLE6 | transducin-like enhancer of split 6 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNPO2 | transportin 2 |
| TPMT | thiopurine S-methyltransferase |
| TRIM21 | tripartite motif containing 21 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSC22D2 | TSC22 domain family, member 2 |
| TUBA4B | tubulin, alpha 4b |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF609 | zinc finger protein 609 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AEN | apoptosis enhancing nuclease |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDON | cell adhesion associated, oncogene regulated |
| CISH | cytokine inducible SH2-containing protein |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DRD1 | dopamine receptor D1 |
| EFNA3 | ephrin-A3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EVPL | envoplakin |
| FADS2 | fatty acid desaturase 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRK | fyn-related Src family tyrosine kinase |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HYI | hydroxypyruvate isomerase (putative) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT140 | intraflagellar transport 140 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF9 | interferon regulatory factor 9 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0355 | KIAA0355 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LPXN | leupaxin |
| MCOLN3 | mucolipin 3 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MVD | mevalonate (diphospho) decarboxylase |
| MVP | major vault protein |
| NEK11 | NIMA-related kinase 11 |
| NLRX1 | NLR family member X1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RCAN3 | RCAN family member 3 |
| RECQL4 | RecQ protein-like 4 |
| RFXAP | regulatory factor X-associated protein |
| RNF43 | ring finger protein 43 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TDRD1 | tudor domain containing 1 |
| TH | tyrosine hydroxylase |
| THBS3 | thrombospondin 3 |
| TMEM39B | transmembrane protein 39B |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNS2 | tensin 2 |
| TOM1 | target of myb1 (chicken) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| USP20 | ubiquitin specific peptidase 20 |
| VLDLR | very low density lipoprotein receptor |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF350 | zinc finger protein 350 |
| ZNF408 | zinc finger protein 408 |
| ZNF492 | zinc finger protein 492 |
| ZNF574 | zinc finger protein 574 |
| ZNF668 | zinc finger protein 668 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
