| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the proxyphylline-7290 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACVR1B | activin A receptor, type IB |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| ATXN2L | ataxin 2-like |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BIN1 | bridging integrator 1 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDK3 | cyclin-dependent kinase 3 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EFNB1 | ephrin-B1 |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ERCC4 | excision repair cross-complementation group 4 |
| FAS | Fas cell surface death receptor |
| FLJ11292 | |
| GIPR | gastric inhibitory polypeptide receptor |
| GPR107 | G protein-coupled receptor 107 |
| GPR157 | G protein-coupled receptor 157 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFT54 | intraflagellar transport 54 |
| IL15 | interleukin 15 |
| INO80B | INO80 complex subunit B |
| JAG1 | jagged 1 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KHK | ketohexokinase (fructokinase) |
| KLHL29 | kelch-like family member 29 |
| LIMK1 | LIM domain kinase 1 |
| LRRC41 | leucine rich repeat containing 41 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MARS | methionyl-tRNA synthetase |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED25 | mediator complex subunit 25 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MST1 | macrophage stimulating 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC1 | mucin 1, cell surface associated |
| NDE1 | nudE neurodevelopment protein 1 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NINJ1 | ninjurin 1 |
| NOTCH1 | notch 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRR15L | proline rich 15-like |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PVR | poliovirus receptor |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| REST | RE1-silencing transcription factor |
| RGS10 | regulator of G-protein signaling 10 |
| RUNDC3B | RUN domain containing 3B |
| S100A13 | S100 calcium binding protein A13 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCN3A | sodium channel, voltage gated, type III alpha subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERHL2 | serine hydrolase-like 2 |
| SH2D2A | SH2 domain containing 2A |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPO11 | SPO11 meiotic protein covalently bound to DSB |
| SPRR2B | small proline-rich protein 2B |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TBC1D22A | TBC1 domain family, member 22A |
| TEX261 | testis expressed 261 |
| TLN2 | talin 2 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM180 | transmembrane protein 180 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF276 | zinc finger protein 276 |
| ZNF391 | zinc finger protein 391 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARMC6 | armadillo repeat containing 6 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BAK1 | BCL2-antagonist/killer 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCS | copper chaperone for superoxide dismutase |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEP112 | centrosomal protein 112kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN15 | claudin 15 |
| CLDN3 | claudin 3 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CTSK | cathepsin K |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DLL3 | delta-like 3 (Drosophila) |
| EGF | epidermal growth factor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESM1 | endothelial cell-specific molecule 1 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
| FAM50B | family with sequence similarity 50, member B |
| FPGS | folylpolyglutamate synthase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPATCH1 | G patch domain containing 1 |
| HDAC5 | histone deacetylase 5 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| ICK | intestinal cell (MAK-like) kinase |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF9 | interferon regulatory factor 9 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KRT6A | keratin 6A, type II |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LUC7L | LUC7-like (S. cerevisiae) |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPST | mercaptopyruvate sulfurtransferase |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLD2 | phospholipase D2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLI | polymerase (DNA directed) iota |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SHPK | sedoheptulokinase |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNX15 | sorting nexin 15 |
| SP140L | SP140 nuclear body protein-like |
| SPAG4 | sperm associated antigen 4 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAR | steroidogenic acute regulatory protein |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THBS3 | thrombospondin 3 |
| TNS2 | tensin 2 |
| TRIM26 | tripartite motif containing 26 |
| TRIM45 | tripartite motif containing 45 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TYK2 | tyrosine kinase 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP6NL | USP6 N-terminal like |
| WDR91 | WD repeat domain 91 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF408 | zinc finger protein 408 |
| ZNF415 | zinc finger protein 415 |
| ZNF668 | zinc finger protein 668 |
| ZNF83 | zinc finger protein 83 |
