pseudopelletierine-1774 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the pseudopelletierine-1774 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACRV1 acrosomal vesicle protein 1
ADAM8 ADAM metallopeptidase domain 8
ADGRE1 adhesion G protein-coupled receptor E1
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALOXE3 arachidonate lipoxygenase 3
ASPH aspartate beta-hydroxylase
ATXN7 ataxin 7
BAX BCL2-associated X protein
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC94 coiled-coil domain containing 94
CDK13 cyclin-dependent kinase 13
CEL carboxyl ester lipase
CLCN7 chloride channel, voltage-sensitive 7
CLPTM1 cleft lip and palate associated transmembrane protein 1
CPNE1 copine I
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSNK1D casein kinase 1, delta
CTRL chymotrypsin-like
CTSZ cathepsin Z
CXCR3 chemokine (C-X-C motif) receptor 3
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP8 dual specificity phosphatase 8
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECM1 extracellular matrix protein 1
EGR1 early growth response 1
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ELMO2 engulfment and cell motility 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FAM178A family with sequence similarity 178, member A
FANCA Fanconi anemia, complementation group A
FGL2 fibrinogen-like 2
FLOT1 flotillin 1
FSCN3 fascin actin-bundling protein 3, testicular
GATAD2A GATA zinc finger domain containing 2A
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIMAP5 GTPase, IMAP family member 5
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPSM3 G-protein signaling modulator 3
HIPK2 homeodomain interacting protein kinase 2
HOOK2 hook microtubule-tethering protein 2
HP haptoglobin
IDS iduronate 2-sulfatase
ITGB5 integrin, beta 5
ITGB7 integrin, beta 7
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KPNA6 karyopherin alpha 6 (importin alpha 7)
LAT2 linker for activation of T cells family, member 2
LUZP1 leucine zipper protein 1
MAGED2 melanoma antigen family D2
MB myoglobin
MED9 mediator complex subunit 9
MTERF4 mitochondrial transcription termination factor 4
MYRF myelin regulatory factor
NKX3-1 NK3 homeobox 1
NOP16 NOP16 nucleolar protein
NPPA natriuretic peptide A
NTNG1 netrin G1
OGG1 8-oxoguanine DNA glycosylase
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PDCL phosducin-like
PIDD1 p53-induced death domain protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PISD phosphatidylserine decarboxylase
PLEC plectin
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
PPARD peroxisome proliferator-activated receptor delta
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRB1 proline-rich protein BstNI subfamily 1
PSG3 pregnancy specific beta-1-glycoprotein 3
PTCRA pre T-cell antigen receptor alpha
PTPRO protein tyrosine phosphatase, receptor type, O
RGS12 regulator of G-protein signaling 12
RHOBTB3 Rho-related BTB domain containing 3
RPS21 ribosomal protein S21
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A12 S100 calcium binding protein A12
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
ST7 suppression of tumorigenicity 7
TBC1D29 TBC1 domain family, member 29
TBL1X transducin (beta)-like 1X-linked
TEX40 testis expressed 40
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TP53I11 tumor protein p53 inducible protein 11
TRAF1 TNF receptor-associated factor 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZBTB20 zinc finger and BTB domain containing 20
ZBTB22 zinc finger and BTB domain containing 22
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF395 zinc finger protein 395
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD3 abhydrolase domain containing 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P2 annexin A2 pseudogene 2
ARL4A ADP-ribosylation factor-like 4A
ARMC1 armadillo repeat containing 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ATAD2B ATPase family, AAA domain containing 2B
ATXN2 ataxin 2
BTNL3 butyrophilin-like 3
C11ORF73 chromosome 11 open reading frame 73
C14ORF159 chromosome 14 open reading frame 159
C5ORF28 chromosome 5 open reading frame 28
CASZ1 castor zinc finger 1
CD33 CD33 molecule
CDK9 cyclin-dependent kinase 9
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLASP1 cytoplasmic linker associated protein 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DRD5 dopamine receptor D5
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EMC9 ER membrane protein complex subunit 9
GEMIN6 gem (nuclear organelle) associated protein 6
GTF2I general transcription factor IIi
H2BFS H2B histone family, member S (pseudogene)
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0196 KIAA0196
KIAA1598
KIF18A kinesin family member 18A
KIFC1 kinesin family member C1
KPNA4 karyopherin alpha 4 (importin alpha 3)
LAS1L LAS1-like (S. cerevisiae)
LHFPL2 lipoma HMGIC fusion partner-like 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGOHB mago-nashi homolog B (Drosophila)
MCM10 minichromosome maintenance complex component 10
MCRS1 microspherule protein 1
MCTP1 multiple C2 domains, transmembrane 1
MED17 mediator complex subunit 17
MMP9 matrix metallopeptidase 9
MON1B MON1 secretory trafficking family member B
MPDU1 mannose-P-dolichol utilization defect 1
MRPL24 mitochondrial ribosomal protein L24
MXRA8 matrix-remodelling associated 8
MYL12B myosin, light chain 12B, regulatory
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NMD3 NMD3 ribosome export adaptor
NUCB2 nucleobindin 2
PARPBP PARP1 binding protein
PCNXL4 pecanex-like 4 (Drosophila)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHB prohibitin
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRDM13 PR domain containing 13
PRRC1 proline-rich coiled-coil 1
PSAT1 phosphoserine aminotransferase 1
PTBP2 polypyrimidine tract binding protein 2
RABEPK Rab9 effector protein with kelch motifs
RPE ribulose-5-phosphate-3-epimerase
RPL39L ribosomal protein L39-like
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDHAF3 succinate dehydrogenase complex assembly factor 3
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SH2D2A SH2 domain containing 2A
SLC25A40 solute carrier family 25, member 40
SLMO2 slowmo homolog 2 (Drosophila)
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
SNX17 sorting nexin 17
STIP1 stress-induced phosphoprotein 1
STK25 serine/threonine kinase 25
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN2 tectonic family member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UBA5 ubiquitin-like modifier activating enzyme 5
WASF1 WAS protein family, member 1
WDR19 WD repeat domain 19
WDR41 WD repeat domain 41
YEATS4 YEATS domain containing 4
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZNF586 zinc finger protein 586
ZNRD1-AS1 ZNRD1 antisense RNA 1