pseudopelletierine-5828 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the pseudopelletierine-5828 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
AMDHD2 amidohydrolase domain containing 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAX BCL2-associated X protein
C7ORF69 chromosome 7 open reading frame 69
C9ORF156 chromosome 9 open reading frame 156
CCNJL cyclin J-like
CCNT2 cyclin T2
CDK6 cyclin-dependent kinase 6
CDY1 chromodomain protein, Y-linked, 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CROCC ciliary rootlet coiled-coil, rootletin
CSRNP3 cysteine-serine-rich nuclear protein 3
DAPK3 death-associated protein kinase 3
DCN decorin
DMBT1 deleted in malignant brain tumors 1
EML3 echinoderm microtubule associated protein like 3
EPHB2 EPH receptor B2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ETV1 ets variant 1
EVI5 ecotropic viral integration site 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM184A family with sequence similarity 184, member A
FAM50B family with sequence similarity 50, member B
FBXO40 F-box protein 40
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GM2A GM2 ganglioside activator
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC1 host cell factor C1
HIRA histone cell cycle regulator
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSDL2 hydroxysteroid dehydrogenase like 2
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IL1RN interleukin 1 receptor antagonist
INSR insulin receptor
IPCEF1 interaction protein for cytohesin exchange factors 1
ITGB7 integrin, beta 7
KLHL20 kelch-like family member 20
KRT34 keratin 34, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LIG4 ligase IV, DNA, ATP-dependent
LMCD1 LIM and cysteine-rich domains 1
LOC399491
LOC647070 uncharacterized LOC647070
LRP3 low density lipoprotein receptor-related protein 3
MBD4 methyl-CpG binding domain protein 4
MCTP2 multiple C2 domains, transmembrane 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MINK1 misshapen-like kinase 1
MRAS muscle RAS oncogene homolog
NCOA3 nuclear receptor coactivator 3
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOL10 nucleolar protein 10
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PANK3 pantothenate kinase 3
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAD23B RAD23 homolog B (S. cerevisiae)
RPS3A ribosomal protein S3A
SBNO2 strawberry notch homolog 2 (Drosophila)
SDC2 syndecan 2
SGSM3 small G protein signaling modulator 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMR3A submaxillary gland androgen regulated protein 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX13 sorting nexin 13
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STS steroid sulfatase (microsomal), isozyme S
SUGCT succinyl-CoA:glutarate-CoA transferase
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D13 TBC1 domain family, member 13
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCP10L t-complex 10-like
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TSKU tsukushi, small leucine rich proteoglycan
TUBA4B tubulin, alpha 4b
TXLNG taxilin gamma
UNC119 unc-119 homolog (C. elegans)
VCAN versican
ZFAND5 zinc finger, AN1-type domain 5
ZMYM5 zinc finger, MYM-type 5
ZNF230 zinc finger protein 230
ZNF280A zinc finger protein 280A
ZNF337 zinc finger protein 337
ZNF440 zinc finger protein 440
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD4 abhydrolase domain containing 4
ACVR2B activin A receptor, type IIB
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
ANAPC2 anaphase promoting complex subunit 2
ASB7 ankyrin repeat and SOCS box containing 7
ATAD3A ATPase family, AAA domain containing 3A
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BIRC3 baculoviral IAP repeat containing 3
BTBD2 BTB (POZ) domain containing 2
C17ORF85 chromosome 17 open reading frame 85
C1ORF159 chromosome 1 open reading frame 159
C2ORF42 chromosome 2 open reading frame 42
CAPN5 calpain 5
CCDC69 coiled-coil domain containing 69
CDKL3 cyclin-dependent kinase-like 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHML choroideremia-like (Rab escort protein 2)
CHRM3 cholinergic receptor, muscarinic 3
CHST10 carbohydrate sulfotransferase 10
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
COBL cordon-bleu WH2 repeat protein
CPEB1 cytoplasmic polyadenylation element binding protein 1
CXCL3 chemokine (C-X-C motif) ligand 3
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPTOR DEP domain containing MTOR-interacting protein
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAL4 dynein, axonemal, light chain 4
DNM1 dynamin 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
E4F1 E4F transcription factor 1
EDC3 enhancer of mRNA decapping 3
EFNA1 ephrin-A1
EGF epidermal growth factor
EMC6 ER membrane protein complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FA2H fatty acid 2-hydroxylase
FGGY FGGY carbohydrate kinase domain containing
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLCE glucuronic acid epimerase
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HINFP histone H4 transcription factor
HIST1H2AM histone cluster 1, H2am
HPS6 Hermansky-Pudlak syndrome 6
IL17RB interleukin 17 receptor B
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIAA0922 KIAA0922
KIAA1462 KIAA1462
LRRK1 leucine-rich repeat kinase 1
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MAPK12 mitogen-activated protein kinase 12
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NBAS neuroblastoma amplified sequence
NDE1 nudE neurodevelopment protein 1
NHEJ1 nonhomologous end-joining factor 1
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
NUBP2 nucleotide binding protein 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXPH4 neurexophilin 4
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PAQR6 progestin and adipoQ receptor family member VI
PDLIM2 PDZ and LIM domain 2 (mystique)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLCD1 phospholipase C, delta 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PORCN porcupine homolog (Drosophila)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PUS1 pseudouridylate synthase 1
RAD9A RAD9 homolog A (S. pombe)
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
SDC3 syndecan 3
SETBP1 SET binding protein 1
SLC41A3 solute carrier family 41, member 3
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SNPH syntaphilin
SNX16 sorting nexin 16
STK25 serine/threonine kinase 25
TAOK1 TAO kinase 1
TGFB3 transforming growth factor, beta 3
TMCC2 transmembrane and coiled-coil domain family 2
TNS2 tensin 2
TRPM2 transient receptor potential cation channel, subfamily M, member 2
USP21 ubiquitin specific peptidase 21
USP27X ubiquitin specific peptidase 27, X-linked
WDR18 WD repeat domain 18
YIPF1 Yip1 domain family, member 1
ZBED1 zinc finger, BED-type containing 1
ZNF8 zinc finger protein 8