psoriasis Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A skin abnormality characterized by redness and irritation, with thick, red skin that displays flaky, silver-white patches (scales). (Human Phenotype Ontology, HP_0003765)
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38 genes associated with the disease psoriasis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HLA-C major histocompatibility complex, class I, C 2.61413
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 1.68372
MICB MHC class I polypeptide-related sequence B 1.61356
IL12B interleukin 12B 1.39702
ANXA6 annexin A6 1.39702
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.35143
TRAF3IP2 TRAF3 interacting protein 2 1.17894
IL13 interleukin 13 1.04495
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 0.965481
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.790827
CAST calpastatin 0.774217
ERAP1 endoplasmic reticulum aminopeptidase 1 0.774217
TYK2 tyrosine kinase 2 0.7623
NOS2 nitric oxide synthase 2, inducible 0.7623
LCE3C late cornified envelope 3C 0.682635
FBXL19 F-box and leucine-rich repeat protein 19 0.63666
STAT2 signal transducer and activator of transcription 2, 113kDa 0.63207
HLA-B major histocompatibility complex, class I, B 0.63207
LCE3A late cornified envelope 3A 0.52461
SPATA2 spermatogenesis associated 2 0.52461
PUS10 pseudouridylate synthase 10 0.52461
KIAA0391 KIAA0391 0.486425
IL23R interleukin 23 receptor 0.464771
IFNLR1 interferon, lambda receptor 1 0.4215
FAM27L family with sequence similarity 27-like 0.403461
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.368757
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.285417
RPS26 ribosomal protein S26 0.256228
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.256228
DYTN dystrotelin 0.197766
NKX2-6 NK2 homeobox 6 0.197766
STK32A serine/threonine kinase 32A 0.197766
RNF114 ring finger protein 114 0.197766
COG6 component of oligomeric golgi complex 6 0.197766
OAF OAF homolog (Drosophila) 0.15771
RGS6 regulator of G-protein signaling 6 0.080593
TSC1 tuberous sclerosis 1 0.080593
BCL7C B-cell CLL/lymphoma 7C 0.052255