psoriasis Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A skin abnormality characterized by redness and irritation, with thick, red skin that displays flaky, silver-white patches (scales). (Human Phenotype Ontology, HP_0003765)
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Genes

141 genes associated with the disease psoriasis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD16A abhydrolase domain containing 16A
ACE angiotensin I converting enzyme
ADAM33 ADAM metallopeptidase domain 33
AGER advanced glycosylation end product-specific receptor
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
APOE apolipoprotein E
C2 complement component 2
C6ORF10 chromosome 6 open reading frame 10
CAST calpastatin
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL2 chemokine (C-C motif) ligand 2
CD226 CD226 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDSN corneodesmosin
COG6 component of oligomeric golgi complex 6
CSMD1 CUB and Sushi multiple domains 1
CSTA cystatin A (stefin A)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDR1 discoidin domain receptor tyrosine kinase 1
DEFB1 defensin, beta 1
DPCR1 diffuse panbronchiolitis critical region 1
EDN1 endothelin 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FBXL19 F-box and leucine-rich repeat protein 19
FLG filaggrin
GJB2 gap junction protein, beta 2, 26kDa
GPSM3 G-protein signaling modulator 3
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HCP5 HLA complex P5 (non-protein coding)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFIH1 interferon induced with helicase C domain 1
IFNG interferon, gamma
IFNLR1 interferon, lambda receptor 1
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL20RA interleukin 20 receptor, alpha
IL20RB interleukin 20 receptor beta
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IRF2 interferon regulatory factor 2
IRF5 interferon regulatory factor 5
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KIAA0391 KIAA0391
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LCE3A late cornified envelope 3A
LCE3B late cornified envelope 3B
LCE3C late cornified envelope 3C
LCE3D late cornified envelope 3D
LST1 leukocyte specific transcript 1
LTA lymphotoxin alpha
MCCD1 mitochondrial coiled-coil domain 1
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP2 matrix metallopeptidase 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC21 mucin 21, cell surface associated
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOTCH4 notch 4
NQO1 NAD(P)H dehydrogenase, quinone 1
PBX2 pre-B-cell leukemia homeobox 2
POU5F1 POU class 5 homeobox 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSORS1C1 psoriasis susceptibility 1 candidate 1
PSORS1C2 psoriasis susceptibility 1 candidate 2
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding)
PSORS5 psoriasis susceptibility 5
PSORS6 psoriasis susceptibility 6
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTTG1 pituitary tumor-transforming 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RNF114 ring finger protein 114
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RUNX1 runt-related transcription factor 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPATA2 spermatogenesis associated 2
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT4 signal transducer and activator of transcription 4
SUMO4 small ubiquitin-like modifier 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TCF19 transcription factor 19
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
TNXB tenascin XB
TRAF3IP2 TRAF3 interacting protein 2
TRIM15 tripartite motif containing 15
TRIM40 tripartite motif containing 40
TSC1 tuberous sclerosis 1
TYK2 tyrosine kinase 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
ZNF816 zinc finger protein 816
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