pth Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description parathyroid hormone|The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5741)
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Genes

50 genes co-occuring with the biological term pth in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARRB2 arrestin, beta 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BAD BCL2-associated agonist of cell death
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
CASR calcium-sensing receptor
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
ELF4 E74-like factor 4 (ets domain transcription factor)
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
GC group-specific component (vitamin D binding protein)
GCM2 glial cells missing homolog 2 (Drosophila)
HNF1B HNF1 homeobox B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IBSP integrin-binding sialoprotein
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL21R interleukin 21 receptor
KHSRP KH-type splicing regulatory protein
KL klotho
LRP6 low density lipoprotein receptor-related protein 6
MAB21L1 mab-21-like 1 (C. elegans)
MAPK8 mitogen-activated protein kinase 8
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NFYA nuclear transcription factor Y, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
POSTN periostin, osteoblast specific factor
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCB protein kinase C, beta
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTH2R parathyroid hormone 2 receptor
PTHLH parathyroid hormone-like hormone
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TSPO translocator protein (18kDa)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor