purified Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

349 genes co-occuring with the biological term purified in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACTA2 actin, alpha 2, smooth muscle, aorta
ADA adenosine deaminase
ADAM10 ADAM metallopeptidase domain 10
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AGO2 argonaute RISC catalytic component 2
AGXT alanine-glyoxylate aminotransferase
AHI1 Abelson helper integration site 1
AIRE autoimmune regulator
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ANO1 anoctamin 1, calcium activated chloride channel
AOX1 aldehyde oxidase 1
APCS amyloid P component, serum
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APIP APAF1 interacting protein
APOB apolipoprotein B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC2 apolipoprotein C-II
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AREG amphiregulin
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARG1 arginase 1
ARID1A AT rich interactive domain 1A (SWI-like)
AS3MT arsenite methyltransferase
ASB9 ankyrin repeat and SOCS box containing 9
ASPA aspartoacylase
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATR ATR serine/threonine kinase
BARD1 BRCA1 associated RING domain 1
BCL6 B-cell CLL/lymphoma 6
BCO1 beta-carotene oxygenase 1
BMP15 bone morphogenetic protein 15
BRCA1 breast cancer 1, early onset
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
C4B complement component 4B (Chido blood group)
C4BPB complement component 4 binding protein, beta
CALCA calcitonin-related polypeptide alpha
CARD11 caspase recruitment domain family, member 11
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CD14 CD14 molecule
CD151 CD151 molecule (Raph blood group)
CD177 CD177 molecule
CD274 CD274 molecule
CD4 CD4 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDC6 cell division cycle 6
CEP70 centrosomal protein 70kDa
CETN2 centrin, EF-hand protein, 2
CFH complement factor H
CFI complement factor I
CGB chorionic gonadotropin, beta polypeptide
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHKA choline kinase alpha
CHRM1 cholinergic receptor, muscarinic 1
CKAP4 cytoskeleton-associated protein 4
CLEC7A C-type lectin domain family 7, member A
CMA1 chymase 1, mast cell
CNOT7 CCR4-NOT transcription complex, subunit 7
CORO2A coronin, actin binding protein, 2A
CPB2 carboxypeptidase B2 (plasma)
CRCP CGRP receptor component
CRISP2 cysteine-rich secretory protein 2
CRP C-reactive protein, pentraxin-related
CRYM crystallin, mu
CTCF CCCTC-binding factor (zinc finger protein)
CTSB cathepsin B
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DICER1 dicer 1, ribonuclease type III
DKC1 dyskeratosis congenita 1, dyskerin
DNA2 DNA replication helicase/nuclease 2
EDNRA endothelin receptor type A
EFNA1 ephrin-A1
EFNA3 ephrin-A3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ENO2 enolase 2 (gamma, neuronal)
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
EPO erythropoietin
ERCC6 excision repair cross-complementation group 6
ESR1 estrogen receptor 1
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F5 coagulation factor V (proaccelerin, labile factor)
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGB fibrinogen beta chain
FGF1 fibroblast growth factor 1 (acidic)
FGF21 fibroblast growth factor 21
FHOD1 formin homology 2 domain containing 1
FLNA filamin A, alpha
FLOT1 flotillin 1
FLT3LG fms-related tyrosine kinase 3 ligand
FOXP3 forkhead box P3
FUCA1 fucosidase, alpha-L- 1, tissue
FURIN furin (paired basic amino acid cleaving enzyme)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G6PD glucose-6-phosphate dehydrogenase
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADD45G growth arrest and DNA-damage-inducible, gamma
GDAP1 ganglioside induced differentiation associated protein 1
GDF9 growth differentiation factor 9
GEMIN2 gem (nuclear organelle) associated protein 2
GEMIN7 gem (nuclear organelle) associated protein 7
GFER growth factor, augmenter of liver regeneration
GFI1 growth factor independent 1 transcription repressor
GHSR growth hormone secretagogue receptor
GMPR2 guanosine monophosphate reductase 2
GOPC golgi-associated PDZ and coiled-coil motif containing
GP6 glycoprotein VI (platelet)
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSR glutathione reductase
GSTP1 glutathione S-transferase pi 1
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GYPC glycophorin C (Gerbich blood group)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBA1 hemoglobin, alpha 1
HEBP1 heme binding protein 1
HINFP histone H4 transcription factor
HMGB1 high mobility group box 1
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPB1 heat shock 27kDa protein 1
HSPG2 heparan sulfate proteoglycan 2
HTT huntingtin
HVCN1 hydrogen voltage gated channel 1
HYAL1 hyaluronoglucosaminidase 1
HYAL2 hyaluronoglucosaminidase 2
IDO1 indoleamine 2,3-dioxygenase 1
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL1R1 interleukin 1 receptor, type I
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
IL7 interleukin 7
INS insulin
ISL1 ISL LIM homeobox 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA9 integrin, alpha 9
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
KAT2A K(lysine) acetyltransferase 2A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KEAP1 kelch-like ECH-associated protein 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KMT2A lysine (K)-specific methyltransferase 2A
LACRT lacritin
LALBA lactalbumin, alpha-
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LAMC2 laminin, gamma 2
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGALS3 lectin, galactoside-binding, soluble, 3
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LMNA lamin A/C
LOXL2 lysyl oxidase-like 2
LPL lipoprotein lipase
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
LSM10 LSM10, U7 small nuclear RNA associated
LTB4R2 leukotriene B4 receptor 2
LY96 lymphocyte antigen 96
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK14 mitogen-activated protein kinase 14
MAPK9 mitogen-activated protein kinase 9
MBP myelin basic protein
MCAM melanoma cell adhesion molecule
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MDK midkine (neurite growth-promoting factor 2)
MGMT O-6-methylguanine-DNA methyltransferase
MGST2 microsomal glutathione S-transferase 2
MIEF1 mitochondrial elongation factor 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MSMB microseminoprotein, beta-
MTRF1 mitochondrial translational release factor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYH11 myosin, heavy chain 11, smooth muscle
NADK NAD kinase
NAGS N-acetylglutamate synthase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NPC1 Niemann-Pick disease, type C1
NPR3 natriuretic peptide receptor 3
NPSA novel prostate-specific antigen
OGG1 8-oxoguanine DNA glycosylase
ORC1 origin recognition complex, subunit 1
OXT oxytocin/neurophysin I prepropeptide
PAH phenylalanine hydroxylase
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCNA proliferating cell nuclear antigen
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD1 programmed cell death 1
PDCD6IP programmed cell death 6 interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA5 protein disulfide isomerase family A, member 5
PGM2 phosphoglucomutase 2
PIGR polymeric immunoglobulin receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCH2 phospholipase C, eta 2
PML promyelocytic leukemia
PNLIPRP2 pancreatic lipase-related protein 2
POLB polymerase (DNA directed), beta
POLM polymerase (DNA directed), mu
POLQ polymerase (DNA directed), theta
PON1 paraoxonase 1
PON3 paraoxonase 3
PPARG peroxisome proliferator-activated receptor gamma
PPOX protoporphyrinogen oxidase
PRCP prolylcarboxypeptidase (angiotensinase C)
PREPL prolyl endopeptidase-like
PRL prolactin
PRPF19 pre-mRNA processing factor 19
PSENEN presenilin enhancer gamma secretase subunit
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PTMA prothymosin, alpha
PTN pleiotrophin
RAB6C RAB6C, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAE1 ribonucleic acid export 1
RALBP1 ralA binding protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RECQL4 RecQ protein-like 4
REV1 REV1, polymerase (DNA directed)
RHD Rh blood group, D antigen
RHEB Ras homolog enriched in brain
RHOC ras homolog family member C
RNF216 ring finger protein 216
RPA1 replication protein A1, 70kDa
S100A13 S100 calcium binding protein A13
S100A7A S100 calcium binding protein A7A
SAA1 serum amyloid A1
SARS seryl-tRNA synthetase
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCRN1 secernin 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SFTPD surfactant protein D
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC38A2 solute carrier family 38, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMC2 structural maintenance of chromosomes 2
SMN1 survival of motor neuron 1, telomeric
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPIN1 spindlin 1
STS steroid sulfatase (microsomal), isozyme S
SULF2 sulfatase 2
SUOX sulfite oxidase
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SYT16 synaptotagmin XVI
TACSTD2 tumor-associated calcium signal transducer 2
TARBP2 TAR (HIV-1) RNA binding protein 2
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBP TATA box binding protein
TBXA2R thromboxane A2 receptor
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THTPA thiamine triphosphatase
THYN1 thymocyte nuclear protein 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TMPRSS5 transmembrane protease, serine 5
TNF tumor necrosis factor
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TOB1 transducer of ERBB2, 1
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TPI1 triosephosphate isomerase 1
TPST1 tyrosylprotein sulfotransferase 1
TPT1 tumor protein, translationally-controlled 1
TRAF4 TNF receptor-associated factor 4
TRIM28 tripartite motif containing 28
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TXNL4B thioredoxin-like 4B
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBTD1 ubiquitin domain containing 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGCG UDP-glucose ceramide glucosyltransferase
UGDH UDP-glucose 6-dehydrogenase
UNG uracil-DNA glycosylase
VKORC1 vitamin K epoxide reductase complex, subunit 1
VN1R1 vomeronasal 1 receptor 1
VTN vitronectin
VWF von Willebrand factor
WRN Werner syndrome, RecQ helicase-like
YAP1 Yes-associated protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB7A zinc finger and BTB domain containing 7A