purine nucleobase biosynthetic process Gene Set

Dataset	GO Biological Process Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine. (Gene Ontology, GO_0009113)
External Link	http://amigo.geneontology.org/amigo/term/GO_0009113
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Genes

6 genes participating in the purine nucleobase biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol	Name
GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GMPS	guanine monphosphate synthase
PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PRPS1	phosphoribosyl pyrophosphate synthetase 1
SHMT1	serine hydroxymethyltransferase 1 (soluble)
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)