The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar. (Gene Ontology, GO_0034033)
11 genes participating in the purine nucleoside bisphosphate biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.