purine nucleotide biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. (Gene Ontology, GO_0006164)
External Link http://amigo.geneontology.org/amigo/term/GO:0006164
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Genes

21 genes participating in the purine nucleotide biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADA adenosine deaminase
ADSL adenylosuccinate lyase
COASY CoA synthase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HPRT1 hypoxanthine phosphoribosyltransferase 1
KYNU kynureninase
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
NADK NAD kinase
NADSYN1 NAD synthetase 1
NAMPT nicotinamide phosphoribosyltransferase
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
PFAS phosphoribosylformylglycinamidine synthase
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
QPRT quinolinate phosphoribosyltransferase
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7