purine-rich negative regulatory element binding Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes. (Gene Ontology, GO_0032422)
External Link http://amigo.geneontology.org/amigo/term/GO:0032422
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Genes

4 genes performing the purine-rich negative regulatory element binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
PURA purine-rich element binding protein A
PURB purine-rich element binding protein B
PURG purine-rich element binding protein G