| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the puromycin-2448 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 |
| AREG | amphiregulin |
| AURKA | aurora kinase A |
| AVIL | advillin |
| BAG3 | BCL2-associated athanogene 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD70 | CD70 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHN2 | chimerin 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CREM | cAMP responsive element modulator |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| FAS | Fas cell surface death receptor |
| FCAR | Fc fragment of IgA receptor |
| FCMR | Fc fragment of IgM receptor |
| FKBP4 | FK506 binding protein 4, 59kDa |
| G0S2 | G0/G1 switch 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HMOX1 | heme oxygenase 1 |
| HOXA1 | homeobox A1 |
| HSPA4 | heat shock 70kDa protein 4 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER5 | immediate early response 5 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL1R1 | interleukin 1 receptor, type I |
| IL1RN | interleukin 1 receptor antagonist |
| IL24 | interleukin 24 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KIAA0226L | KIAA0226-like |
| KYNU | kynureninase |
| LAMB3 | laminin, beta 3 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MCL1 | myeloid cell leukemia 1 |
| MFAP3 | microfibrillar-associated protein 3 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OSM | oncostatin M |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLK4 | polo-like kinase 4 |
| PLSCR1 | phospholipid scramblase 1 |
| PPID | peptidylprolyl isomerase D |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SIK3 | SIK family kinase 3 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| ST20 | suppressor of tumorigenicity 20 |
| STIP1 | stress-induced phosphoprotein 1 |
| THAP10 | THAP domain containing 10 |
| THBS1 | thrombospondin 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TRIM23 | tripartite motif containing 23 |
| TXNIP | thioredoxin interacting protein |
| ULBP2 | UL16 binding protein 2 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BRD9 | bromodomain containing 9 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1ORF216 | chromosome 1 open reading frame 216 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CBX6 | chromobox homolog 6 |
| CBX7 | chromobox homolog 7 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNE1 | cyclin E1 |
| CD14 | CD14 molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CECR5 | cat eye syndrome chromosome region, candidate 5 |
| CEP72 | centrosomal protein 72kDa |
| CEP97 | centrosomal protein 97kDa |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CTSG | cathepsin G |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| FAM102A | family with sequence similarity 102, member A |
| FAM57A | family with sequence similarity 57, member A |
| FGL1 | fibrinogen-like 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GFI1 | growth factor independent 1 transcription repressor |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRAMD4 | GRAM domain containing 4 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| INSIG1 | insulin induced gene 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KLF11 | Kruppel-like factor 11 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| METTL1 | methyltransferase like 1 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFE2 | nuclear factor, erythroid 2 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PMM2 | phosphomannomutase 2 |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H |
| PPAN | peter pan homolog (Drosophila) |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PRDM13 | PR domain containing 13 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR3 | proline rich 3 |
| PRSS53 | protease, serine, 53 |
| PRTN3 | proteinase 3 |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RGS19 | regulator of G-protein signaling 19 |
| RNF44 | ring finger protein 44 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RUSC1 | RUN and SH3 domain containing 1 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SQLE | squalene epoxidase |
| STRA13 | stimulated by retinoic acid 13 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TERT | telomerase reverse transcriptase |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TNF | tumor necrosis factor |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TSPAN32 | tetraspanin 32 |
| TSPAN5 | tetraspanin 5 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| TUBA3C | tubulin, alpha 3c |
| UNG | uracil-DNA glycosylase |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR43 | WD repeat domain 43 |
| ZNF529 | zinc finger protein 529 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
