puromycin-3310 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the puromycin-3310 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMOTL2 angiomotin like 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
C1ORF54 chromosome 1 open reading frame 54
CFLAR CASP8 and FADD-like apoptosis regulator
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
CLDN1 claudin 1
CLGN calmegin
CLIC4 chloride intracellular channel 4
COL16A1 collagen, type XVI, alpha 1
CTGF connective tissue growth factor
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EXPH5 exophilin 5
FGD6 FYVE, RhoGEF and PH domain containing 6
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GRIK5 glutamate receptor, ionotropic, kainate 5
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNGR1 interferon gamma receptor 1
IL23A interleukin 23, alpha subunit p19
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM6A lysine (K)-specific demethylase 6A
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
N4BP2L2 NEDD4 binding protein 2-like 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIL3 nuclear factor, interleukin 3 regulated
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PER1 period circadian clock 1
PER2 period circadian clock 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSPH phosphoserine phosphatase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFPL2 ret finger protein-like 2
SAMD4A sterile alpha motif domain containing 4A
SH3BGR SH3 domain binding glutamate-rich protein
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOCS2 suppressor of cytokine signaling 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRY4 sprouty homolog 4 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TES testin LIM domain protein
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
ULBP1 UL16 binding protein 1
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
WDR33 WD repeat domain 33
ZNF329 zinc finger protein 329

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ACYP1 acylphosphatase 1, erythrocyte (common) type
ACYP2 acylphosphatase 2, muscle type
AIM1 absent in melanoma 1
AKR1C3 aldo-keto reductase family 1, member C3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AMD1 adenosylmethionine decarboxylase 1
ANKRD36 ankyrin repeat domain 36
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASAP1-IT1 ASAP1 intronic transcript 1
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
B3GNT1
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1GALT1C1 C1GALT1-specific chaperone 1
C2ORF27A chromosome 2 open reading frame 27A
CA2 carbonic anhydrase II
CCNE1 cyclin E1
CCNE2 cyclin E2
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CLDN7 claudin 7
COCH cochlin
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ECI2 enoyl-CoA delta isomerase 2
EFNA4 ephrin-A4
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR3 early growth response 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ERN2 endoplasmic reticulum to nucleus signaling 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM64A family with sequence similarity 64, member A
FBXO31 F-box protein 31
FHOD1 formin homology 2 domain containing 1
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GCHFR GTP cyclohydrolase I feedback regulator
GJA1 gap junction protein, alpha 1, 43kDa
HOXC11 homeobox C11
HSPA2 heat shock 70kDa protein 2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
IRX5 iroquois homeobox 5
LINC00115 long intergenic non-protein coding RNA 115
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC20 leucine rich repeat containing 20
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANEA mannosidase, endo-alpha
MATK megakaryocyte-associated tyrosine kinase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCM3 minichromosome maintenance complex component 3
MCM3AP-AS1 MCM3AP antisense RNA 1
MOGS mannosyl-oligosaccharide glucosidase
MVD mevalonate (diphospho) decarboxylase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NOL12 nucleolar protein 12
NPY1R neuropeptide Y receptor Y1
NT5DC2 5'-nucleotidase domain containing 2
PCBP4 poly(rC) binding protein 4
PCDHB3 protocadherin beta 3
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX11A peroxisomal biogenesis factor 11 alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPIF peptidylprolyl isomerase F
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRR15L proline rich 15-like
PRSS23 protease, serine, 23
PTBP2 polypyrimidine tract binding protein 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL10L ribosomal protein L10-like
RPS14P3 ribosomal protein S14 pseudogene 3
SETD6 SET domain containing 6
SFT2D2 SFT2 domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG3 small nucleolar RNA host gene 3
TMEM120B transmembrane protein 120B
TMSB15B thymosin beta 15B
TPBG trophoblast glycoprotein
TPST2 tyrosylprotein sulfotransferase 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBB4B tubulin, beta 4B class IVb
UBL4A ubiquitin-like 4A
UNG uracil-DNA glycosylase
URM1 ubiquitin related modifier 1
WDR4 WD repeat domain 4
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574