puromycin-5310 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the puromycin-5310 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMOTL2 angiomotin like 2
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BCOR BCL6 corepressor
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
BTN2A1 butyrophilin, subfamily 2, member A1
BTN2A2 butyrophilin, subfamily 2, member A2
CD83 CD83 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLK4 CDC-like kinase 4
CSF1 colony stimulating factor 1 (macrophage)
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLX2 distal-less homeobox 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP1 dual specificity phosphatase 1
EFNA1 ephrin-A1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA2 EPH receptor A2
FGD6 FYVE, RhoGEF and PH domain containing 6
FOXO1 forkhead box O1
GADD45A growth arrest and DNA-damage-inducible, alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXC13 homeobox C13
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNGR1 interferon gamma receptor 1
IL6ST interleukin 6 signal transducer
IRF1 interferon regulatory factor 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KDM2A lysine (K)-specific demethylase 2A
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIL3 nuclear factor, interleukin 3 regulated
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKX3-1 NK3 homeobox 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPTN optineurin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTCH1 patched 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
SAMD4A sterile alpha motif domain containing 4A
SERTAD2 SERTA domain containing 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD6 SMAD family member 6
SOCS2 suppressor of cytokine signaling 2
SRCAP Snf2-related CREBBP activator protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNGR3 synaptogyrin 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A
ZNF217 zinc finger protein 217
ZNF408 zinc finger protein 408
ZNF654 zinc finger protein 654
ZYX zyxin

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
AMD1 adenosylmethionine decarboxylase 1
ARMC6 armadillo repeat containing 6
ATP7B ATPase, Cu++ transporting, beta polypeptide
B3GNT1
C10ORF2 chromosome 10 open reading frame 2
C16ORF59 chromosome 16 open reading frame 59
C1GALT1C1 C1GALT1-specific chaperone 1
C1ORF216 chromosome 1 open reading frame 216
CA2 carbonic anhydrase II
CANT1 calcium activated nucleotidase 1
CBX6 chromobox homolog 6
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNG1 cyclin G1
CHPF2 chondroitin polymerizing factor 2
CLDN7 claudin 7
CTDNEP1 CTD nuclear envelope phosphatase 1
CTPS1 CTP synthase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
DNA2 DNA replication helicase/nuclease 2
ECI2 enoyl-CoA delta isomerase 2
EGR3 early growth response 3
FAM127A family with sequence similarity 127, member A
FAM20B family with sequence similarity 20, member B
FAM64A family with sequence similarity 64, member A
FAM69A family with sequence similarity 69, member A
FEN1 flap structure-specific endonuclease 1
FHOD1 formin homology 2 domain containing 1
FUCA1 fucosidase, alpha-L- 1, tissue
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
GJA1 gap junction protein, alpha 1, 43kDa
GLA galactosidase, alpha
GMNN geminin, DNA replication inhibitor
GNPDA1 glucosamine-6-phosphate deaminase 1
GPR19 G protein-coupled receptor 19
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
LAMA5 laminin, alpha 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNB1 lamin B1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LYPD3 LY6/PLAUR domain containing 3
LYRM4 LYR motif containing 4
MANEA mannosidase, endo-alpha
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAT2A methionine adenosyltransferase II, alpha
MATN2 matrilin 2
MCM3AP-AS1 MCM3AP antisense RNA 1
MEPCE methylphosphate capping enzyme
MOGS mannosyl-oligosaccharide glucosidase
MRPL44 mitochondrial ribosomal protein L44
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NMU neuromedin U
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NT5DC2 5'-nucleotidase domain containing 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCNA proliferating cell nuclear antigen
PCOLCE2 procollagen C-endopeptidase enhancer 2
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRR14L proline rich 14-like
PRR15L proline rich 15-like
PRSS23 protease, serine, 23
PSRC1 proline/serine-rich coiled-coil 1
RAB5B RAB5B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
SACS sacsin molecular chaperone
SCAMP4 secretory carrier membrane protein 4
SDC1 syndecan 1
SFN stratifin
SFT2D2 SFT2 domain containing 2
SLC46A3 solute carrier family 46, member 3
SNHG3 small nucleolar RNA host gene 3
SNORA21 small nucleolar RNA, H/ACA box 21
SOX12 SRY (sex determining region Y)-box 12
SRSF2 serine/arginine-rich splicing factor 2
STX10 syntaxin 10
TACC3 transforming, acidic coiled-coil containing protein 3
TESK2 testis-specific kinase 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPBG trophoblast glycoprotein
TSKU tsukushi, small leucine rich proteoglycan
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
UBL4A ubiquitin-like 4A
UNG uracil-DNA glycosylase
WDR6 WD repeat domain 6