puromycin-6711 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the puromycin-6711 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACKR3 atypical chemokine receptor 3
ADCY7 adenylate cyclase 7
ADM adrenomedullin
ALOXE3 arachidonate lipoxygenase 3
ARG2 arginase 2
ARL14 ADP-ribosylation factor-like 14
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BCL3 B-cell CLL/lymphoma 3
BIRC3 baculoviral IAP repeat containing 3
BMP2 bone morphogenetic protein 2
BRAP BRCA1 associated protein
BTN2A2 butyrophilin, subfamily 2, member A2
C18ORF25 chromosome 18 open reading frame 25
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN1 claudin 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DHRS9 dehydrogenase/reductase (SDR family) member 9
DLX2 distal-less homeobox 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EDN1 endothelin 1
EGR2 early growth response 2
ESRRG estrogen-related receptor gamma
FAM13A family with sequence similarity 13, member A
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IL11 interleukin 11
IL6 interleukin 6
IL7R interleukin 7 receptor
ISL1 ISL LIM homeobox 1
JUN jun proto-oncogene
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLF2 Kruppel-like factor 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LIPG lipase, endothelial
MERTK MER proto-oncogene, tyrosine kinase
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MSX1 msh homeobox 1
N4BP2L2 NEDD4 binding protein 2-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OAZ3 ornithine decarboxylase antizyme 3
OXTR oxytocin receptor
PDE4B phosphodiesterase 4B, cAMP-specific
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRKD1 protein kinase D1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFPL2 ret finger protein-like 2
RHOB ras homolog family member B
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC16A6 solute carrier family 16, member 6
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMAD7 SMAD family member 7
STYK1 serine/threonine/tyrosine kinase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPM1 tropomyosin 1 (alpha)
TRIM26 tripartite motif containing 26
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
UBE2I ubiquitin-conjugating enzyme E2I
VWA5A von Willebrand factor A domain containing 5A
ZNF350 zinc finger protein 350
ZNF44 zinc finger protein 44
ZNF442 zinc finger protein 442
ZNF473 zinc finger protein 473
ZNF606 zinc finger protein 606
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BSG basigin (Ok blood group)
C11ORF68 chromosome 11 open reading frame 68
C1GALT1C1 C1GALT1-specific chaperone 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNE2 cyclin E2
CD9 CD9 molecule
CDCA3 cell division cycle associated 3
CLDN4 claudin 4
CLDN7 claudin 7
CPEB1 cytoplasmic polyadenylation element binding protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
EMP3 epithelial membrane protein 3
FABP4 fatty acid binding protein 4, adipocyte
FAM69A family with sequence similarity 69, member A
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FNTB farnesyltransferase, CAAX box, beta
FZD8 frizzled class receptor 8
GBX2 gastrulation brain homeobox 2
GFOD2 glucose-fructose oxidoreductase domain containing 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPX2 glutathione peroxidase 2
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AM histone cluster 1, H2am
HIST3H2A histone cluster 3, H2a
HJURP Holliday junction recognition protein
HMGB3 high mobility group box 3
HYAL2 hyaluronoglucosaminidase 2
HYAL3 hyaluronoglucosaminidase 3
IGFBP6 insulin-like growth factor binding protein 6
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INHBB inhibin, beta B
IPO8 importin 8
KIF14 kinesin family member 14
KLHDC3 kelch domain containing 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC100127972 uncharacterized LOC100127972
LPAR2 lysophosphatidic acid receptor 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MANBA mannosidase, beta A, lysosomal
MAP6D1 MAP6 domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM3 minichromosome maintenance complex component 3
MCRS1 microspherule protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MFSD5 major facilitator superfamily domain containing 5
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MOGS mannosyl-oligosaccharide glucosidase
MPDU1 mannose-P-dolichol utilization defect 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL34 mitochondrial ribosomal protein L34
MSL1 male-specific lethal 1 homolog (Drosophila)
NPM3 nucleophosmin/nucleoplasmin 3
NXT1 nuclear transport factor 2-like export factor 1
OAZ2 ornithine decarboxylase antizyme 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PDIA5 protein disulfide isomerase family A, member 5
PGD phosphogluconate dehydrogenase
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLAT plasminogen activator, tissue
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLM polymerase (DNA directed), mu
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKCD protein kinase C, delta
PRMT7 protein arginine methyltransferase 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PTGES2 prostaglandin E synthase 2
RAB5B RAB5B, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RPL11 ribosomal protein L11
S100A9 S100 calcium binding protein A9
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SKA1 spindle and kinetochore associated complex subunit 1
SLIT2 slit homolog 2 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG3 small nucleolar RNA host gene 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TACC3 transforming, acidic coiled-coil containing protein 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TRAPPC2L trafficking protein particle complex 2-like
TSPAN1 tetraspanin 1
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
ZFYVE21 zinc finger, FYVE domain containing 21
ZMAT5 zinc finger, matrin-type 5