pyrantel-1413 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pyrantel-1413 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACTC1 actin, alpha, cardiac muscle 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALDOB aldolase B, fructose-bisphosphate
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD12 ankyrin repeat domain 12
ASF1A anti-silencing function 1A histone chaperone
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AURKA aurora kinase A
AVL9 AVL9 homolog (S. cerevisiase)
BBIP1 BBSome interacting protein 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF61 chromosome 1 open reading frame 61
CCNE2 cyclin E2
CCR2 chemokine (C-C motif) receptor 2
CCSER2 coiled-coil serine-rich protein 2
CD22 CD22 molecule
CD46 CD46 molecule, complement regulatory protein
CD86 CD86 molecule
CDC5L cell division cycle 5-like
CENPI centromere protein I
CHERP calcium homeostasis endoplasmic reticulum protein
COX5B cytochrome c oxidase subunit Vb
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH1 cytohesin 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DND1 DND microRNA-mediated repression inhibitor 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EIF5B eukaryotic translation initiation factor 5B
EML2 echinoderm microtubule associated protein like 2
ESR2 estrogen receptor 2 (ER beta)
FBXO11 F-box protein 11
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFR2 fibroblast growth factor receptor 2
FN1 fibronectin 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLI3 GLI family zinc finger 3
GPR18 G protein-coupled receptor 18
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRSF1 G-rich RNA sequence binding factor 1
HIST1H4J histone cluster 1, H4j
HOOK2 hook microtubule-tethering protein 2
HRH3 histamine receptor H3
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
IDI2-AS1 IDI2 antisense RNA 1
IER3IP1 immediate early response 3 interacting protein 1
KLF6 Kruppel-like factor 6
MRPS12 mitochondrial ribosomal protein S12
NAT6 N-acetyltransferase 6 (GCN5-related)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIPBL Nipped-B homolog (Drosophila)
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OPHN1 oligophrenin 1
PDCD2 programmed cell death 2
PGK1 phosphoglycerate kinase 1
PIDD1 p53-induced death domain protein 1
PMCH pro-melanin-concentrating hormone
PNOC prepronociceptin
PRRC2C proline-rich coiled-coil 2C
PSG11 pregnancy specific beta-1-glycoprotein 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB2A RAB2A, member RAS oncogene family
RANBP1 RAN binding protein 1
RGS1 regulator of G-protein signaling 1
RHEB Ras homolog enriched in brain
RHOH ras homolog family member H
RPAIN RPA interacting protein
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SRR serine racemase
SRRT serrate, RNA effector molecule
TFG TRK-fused gene
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM45A transmembrane protein 45A
TRAM1 translocation associated membrane protein 1
TXN thioredoxin
TYR tyrosinase
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
WAPAL wings apart-like homolog (Drosophila)
WSB1 WD repeat and SOCS box containing 1
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF224 zinc finger protein 224
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
ACY1 aminoacylase 1
ADGRE5 adhesion G protein-coupled receptor E5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC2 anaphase promoting complex subunit 2
ANKRD40 ankyrin repeat domain 40
ARHGAP4 Rho GTPase activating protein 4
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
AZU1 azurocidin 1
BCL7C B-cell CLL/lymphoma 7C
BCORL1 BCL6 corepressor-like 1
C12ORF10 chromosome 12 open reading frame 10
CAMK1 calcium/calmodulin-dependent protein kinase I
CARD9 caspase recruitment domain family, member 9
CD151 CD151 molecule (Raph blood group)
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CFL1 cofilin 1 (non-muscle)
CIC capicua transcriptional repressor
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COTL1 coactosin-like F-actin binding protein 1
CPSF3L cleavage and polyadenylation specific factor 3-like
CSK c-src tyrosine kinase
CST3 cystatin C
CYC1 cytochrome c-1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKZ diacylglycerol kinase, zeta
DOLK dolichol kinase
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DVL1 dishevelled segment polarity protein 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFHD2 EF-hand domain family, member D2
ELANE elastase, neutrophil expressed
ERCC2 excision repair cross-complementation group 2
ERF Ets2 repressor factor
FAM173A family with sequence similarity 173, member A
FES FES proto-oncogene, tyrosine kinase
FXYD5 FXYD domain containing ion transport regulator 5
GATAD2A GATA zinc finger domain containing 2A
GPS1 G protein pathway suppressor 1
IFITM3 interferon induced transmembrane protein 3
IP6K1 inositol hexakisphosphate kinase 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MACROD1 MACRO domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP7D1 MAP7 domain containing 1
MFSD10 major facilitator superfamily domain containing 10
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MPDU1 mannose-P-dolichol utilization defect 1
MRPL4 mitochondrial ribosomal protein L4
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NELFE negative elongation factor complex member E
NT5DC2 5'-nucleotidase domain containing 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PEF1 penta-EF-hand domain containing 1
PFN1 profilin 1
PHGDH phosphoglycerate dehydrogenase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PPAN peter pan homolog (Drosophila)
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRTN3 proteinase 3
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTOV1 prostate tumor overexpressed 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB4B RAB4B, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RALY RALY heterogeneous nuclear ribonucleoprotein
REPIN1 replication initiator 1
RNH1 ribonuclease/angiogenin inhibitor 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAC3D1 SAC3 domain containing 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B4 splicing factor 3b, subunit 4, 49kDa
SH2B2 SH2B adaptor protein 2
SH3GL1 SH3-domain GRB2-like 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
STXBP2 syntaxin binding protein 2
TBL3 transducin (beta)-like 3
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TECR trans-2,3-enoyl-CoA reductase
TRAPPC12 trafficking protein particle complex 12
TRIM28 tripartite motif containing 28
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSTA3 tissue specific transplantation antigen P35B
TTC31 tetratricopeptide repeat domain 31
UBE2M ubiquitin-conjugating enzyme E2M
UQCRC1 ubiquinol-cytochrome c reductase core protein I
USP20 ubiquitin specific peptidase 20
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
YIPF3 Yip1 domain family, member 3