| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pyrantel-2097 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APOC1 | apolipoprotein C-I |
| ARMC8 | armadillo repeat containing 8 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| AURKA | aurora kinase A |
| BCL9 | B-cell CLL/lymphoma 9 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C1S | complement component 1, s subcomponent |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CEP164 | centrosomal protein 164kDa |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CISH | cytokine inducible SH2-containing protein |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| ETV7 | ets variant 7 |
| FAM169A | family with sequence similarity 169, member A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD4B | FERM domain containing 4B |
| FRMPD4 | FERM and PDZ domain containing 4 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GALR2 | galanin receptor 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HAP1 | huntingtin-associated protein 1 |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIST1H3A | histone cluster 1, H3a |
| HOOK1 | hook microtubule-tethering protein 1 |
| HPN | hepsin |
| HRK | harakiri, BCL2 interacting protein |
| IFNA2 | interferon, alpha 2 |
| IL36RN | interleukin 36 receptor antagonist |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLHL22 | kelch-like family member 22 |
| KLHL23 | kelch-like family member 23 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MEGF9 | multiple EGF-like-domains 9 |
| METTL7A | methyltransferase like 7A |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP9 | matrix metallopeptidase 9 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NXPH4 | neurexophilin 4 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PHF20L1 | PHD finger protein 20-like 1 |
| PHF7 | PHD finger protein 7 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| POU1F1 | POU class 1 homeobox 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PRKD1 | protein kinase D1 |
| PRR14L | proline rich 14-like |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB33A | RAB33A, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASAL2 | RAS protein activator like 2 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGD | Ras-related GTP binding D |
| SCARB1 | scavenger receptor class B, member 1 |
| SELL | selectin L |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SFTPB | surfactant protein B |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STK4 | serine/threonine kinase 4 |
| SYCP2 | synaptonemal complex protein 2 |
| TACR1 | tachykinin receptor 1 |
| TBX2 | T-box 2 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THBD | thrombomodulin |
| TLR4 | toll-like receptor 4 |
| TMEM212 | transmembrane protein 212 |
| TRIM23 | tripartite motif containing 23 |
| UBTD1 | ubiquitin domain containing 1 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VASH2 | vasohibin 2 |
| WDR1 | WD repeat domain 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF358 | zinc finger protein 358 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARL14 | ADP-ribosylation factor-like 14 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| AXIN1 | axin 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCL2L2 | BCL2-like 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| CBR1 | carbonyl reductase 1 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CEP131 | centrosomal protein 131kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CHPF | chondroitin polymerizing factor |
| CLEC16A | C-type lectin domain family 16, member A |
| COQ4 | coenzyme Q4 |
| CORO1A | coronin, actin binding protein, 1A |
| DCLRE1B | DNA cross-link repair 1B |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DEAF1 | DEAF1 transcription factor |
| DNMBP | dynamin binding protein |
| DUSP8 | dual specificity phosphatase 8 |
| EDC3 | enhancer of mRNA decapping 3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| EVPL | envoplakin |
| FANCE | Fanconi anemia, complementation group E |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FZD3 | frizzled class receptor 3 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR176 | G protein-coupled receptor 176 |
| GPR39 | G protein-coupled receptor 39 |
| GPS2 | G protein pathway suppressor 2 |
| GSDMD | gasdermin D |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HINFP | histone H4 transcription factor |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL17RA | interleukin 17 receptor A |
| IRF2 | interferon regulatory factor 2 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| JMJD4 | jumonji domain containing 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0894 | KIAA0894 protein |
| KLC2 | kinesin light chain 2 |
| KRT86 | keratin 86, type II |
| LRRC6 | leucine rich repeat containing 6 |
| MAGEA6 | melanoma antigen family A6 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MUTYH | mutY homolog |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G15 | phospholipase A2, group XV |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POR | P450 (cytochrome) oxidoreductase |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAME | preferentially expressed antigen in melanoma |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PYCARD | PYD and CARD domain containing |
| RBM42 | RNA binding motif protein 42 |
| RGS19 | regulator of G-protein signaling 19 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SIRT2 | sirtuin 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SNTA1 | syntrophin, alpha 1 |
| SNUPN | snurportin 1 |
| SPAG4 | sperm associated antigen 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBL3 | transducin (beta)-like 3 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TMEM132A | transmembrane protein 132A |
| TMEM183A | transmembrane protein 183A |
| TRIM45 | tripartite motif containing 45 |
| TRIM52 | tripartite motif containing 52 |
| TSPYL2 | TSPY-like 2 |
| TUBG2 | tubulin, gamma 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR18 | WD repeat domain 18 |
| WDR76 | WD repeat domain 76 |
| ZNF350 | zinc finger protein 350 |
| ZNF8 | zinc finger protein 8 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
