pyrantel-5088 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the pyrantel-5088 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADGB androglobin
ADGRL2 adhesion G protein-coupled receptor L2
ADORA1 adenosine A1 receptor
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGEL2 angel homolog 2 (Drosophila)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA2P1 annexin A2 pseudogene 1
ARPIN actin-related protein 2/3 complex inhibitor
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CD40 CD40 molecule, TNF receptor superfamily member 5
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CEND1 cell cycle exit and neuronal differentiation 1
CLEC3B C-type lectin domain family 3, member B
CNN1 calponin 1, basic, smooth muscle
COL8A1 collagen, type VIII, alpha 1
COL8A2 collagen, type VIII, alpha 2
CREBZF CREB/ATF bZIP transcription factor
CSF1 colony stimulating factor 1 (macrophage)
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DKKL1 dickkopf-like 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSCAM Down syndrome cell adhesion molecule
ELOVL5 ELOVL fatty acid elongase 5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPYC epiphycan
ETV6 ets variant 6
FGFR2 fibroblast growth factor receptor 2
FOXN3 forkhead box N3
FRS3 fibroblast growth factor receptor substrate 3
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GH1 growth hormone 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM4 glutamate receptor, metabotropic 4
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IBSP integrin-binding sialoprotein
ICA1 islet cell autoantigen 1, 69kDa
IGHM immunoglobulin heavy constant mu
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIDINS220 kinase D-interacting substrate, 220kDa
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL22 kelch-like family member 22
LEF1 lymphoid enhancer-binding factor 1
LINC00574 long intergenic non-protein coding RNA 574
LOX lysyl oxidase
MEGF9 multiple EGF-like-domains 9
MFAP3L microfibrillar-associated protein 3-like
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MUC2 mucin 2, oligomeric mucus/gel-forming
N4BP2L1 NEDD4 binding protein 2-like 1
NCR2 natural cytotoxicity triggering receptor 2
NEB nebulin
NF1 neurofibromin 1
NPPB natriuretic peptide B
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
PARVA parvin, alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDIA2 protein disulfide isomerase family A, member 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMP2 peripheral myelin protein 2
PRB4 proline-rich protein BstNI subfamily 4
PTGDR2 prostaglandin D2 receptor 2
PTH1R parathyroid hormone 1 receptor
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGR retinal G protein coupled receptor
RGS6 regulator of G-protein signaling 6
SCARA3 scavenger receptor class A, member 3
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT5 sirtuin 5
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX10 SRY (sex determining region Y)-box 10
SPRR1A small proline-rich protein 1A
SRSF7 serine/arginine-rich splicing factor 7
SSX1 synovial sarcoma, X breakpoint 1
STRA6 stimulated by retinoic acid 6
SZT2 seizure threshold 2 homolog (mouse)
TBC1D22A TBC1 domain family, member 22A
TBCD tubulin folding cofactor D
TECTA tectorin alpha
TGFB1 transforming growth factor, beta 1
TK2 thymidine kinase 2, mitochondrial
TMEM63A transmembrane protein 63A
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM15 ADAM metallopeptidase domain 15
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA10 annexin A10
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARSJ arylsulfatase family, member J
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAK1 BCL2-antagonist/killer 1
BBS7 Bardet-Biedl syndrome 7
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BTD biotinidase
C11ORF30 chromosome 11 open reading frame 30
CABIN1 calcineurin binding protein 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNT1 cyclin T1
CDIP1 cell death-inducing p53 target 1
CDK6 cyclin-dependent kinase 6
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CHM choroideremia (Rab escort protein 1)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CSRNP3 cysteine-serine-rich nuclear protein 3
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DENND4A DENN/MADD domain containing 4A
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNA3 ephrin-A3
EGF epidermal growth factor
EPHA4 EPH receptor A4
ERCC5 excision repair cross-complementation group 5
ETAA1 Ewing tumor-associated antigen 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM169A family with sequence similarity 169, member A
FBXL7 F-box and leucine-rich repeat protein 7
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDAP1 ganglioside induced differentiation associated protein 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2I general transcription factor IIi
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
IFI6 interferon, alpha-inducible protein 6
IRAK4 interleukin-1 receptor-associated kinase 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LMCD1 LIM and cysteine-rich domains 1
LRP3 low density lipoprotein receptor-related protein 3
MAP9 microtubule-associated protein 9
MED15 mediator complex subunit 15
MGC12488
MON1B MON1 secretory trafficking family member B
MTERF4 mitochondrial transcription termination factor 4
OSMR oncostatin M receptor
PBLD phenazine biosynthesis-like protein domain containing
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKG2 protein kinase, cGMP-dependent, type II
PRMT7 protein arginine methyltransferase 7
PTPN14 protein tyrosine phosphatase, non-receptor type 14
R3HCC1L R3H domain and coiled-coil containing 1-like
RANBP17 RAN binding protein 17
RPL23AP32 ribosomal protein L23a pseudogene 32
RPP25 ribonuclease P/MRP 25kDa subunit
RRAGB Ras-related GTP binding B
SAMD9 sterile alpha motif domain containing 9
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLITRK5 SLIT and NTRK-like family, member 5
SMAD5 SMAD family member 5
SNX16 sorting nexin 16
SOBP sine oculis binding protein homolog (Drosophila)
SPIN1 spindlin 1
SPRYD7 SPRY domain containing 7
STBD1 starch binding domain 1
SYTL2 synaptotagmin-like 2
THBS3 thrombospondin 3
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
USP32 ubiquitin specific peptidase 32
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
YPEL1 yippee-like 1 (Drosophila)
ZBTB6 zinc finger and BTB domain containing 6
ZCCHC10 zinc finger, CCHC domain containing 10
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF33B zinc finger protein 33B
ZNF408 zinc finger protein 408
ZNF415 zinc finger protein 415
ZNF671 zinc finger protein 671
ZW10 zw10 kinetochore protein