pyrantel-5513 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the pyrantel-5513 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADRA1D adrenoceptor alpha 1D
AHI1 Abelson helper integration site 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANGEL2 angel homolog 2 (Drosophila)
ARMCX4 armadillo repeat containing, X-linked 4
ATG13 autophagy related 13
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF80 chromosome 11 open reading frame 80
C14ORF1 chromosome 14 open reading frame 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN7 chloride channel, voltage-sensitive 7
CLIP4 CAP-GLY domain containing linker protein family, member 4
COL1A1 collagen, type I, alpha 1
COL8A2 collagen, type VIII, alpha 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNM3 dynamin 3
FAM120C family with sequence similarity 120C
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
FRMD1 FERM domain containing 1
FXYD2 FXYD domain containing ion transport regulator 2
GAS7 growth arrest-specific 7
GMPR guanosine monophosphate reductase
GPR3 G protein-coupled receptor 3
GRM2 glutamate receptor, metabotropic 2
GRM8 glutamate receptor, metabotropic 8
GSK3A glycogen synthase kinase 3 alpha
GTPBP1 GTP binding protein 1
IFITM1 interferon induced transmembrane protein 1
IGHA1 immunoglobulin heavy constant alpha 1
IL24 interleukin 24
IL36G interleukin 36, gamma
IRS2 insulin receptor substrate 2
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITSN1 intersectin 1 (SH3 domain protein)
KLK2 kallikrein-related peptidase 2
LAMB3 laminin, beta 3
LIG4 ligase IV, DNA, ATP-dependent
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LMF2 lipase maturation factor 2
MCTP1 multiple C2 domains, transmembrane 1
MFAP3L microfibrillar-associated protein 3-like
MKL1 megakaryoblastic leukemia (translocation) 1
MNDA myeloid cell nuclear differentiation antigen
MSR1 macrophage scavenger receptor 1
MTRF1L mitochondrial translational release factor 1-like
MTSS1 metastasis suppressor 1
NEFM neurofilament, medium polypeptide
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NF1 neurofibromin 1
NNAT neuronatin
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OCA2 oculocutaneous albinism II
OSMR oncostatin M receptor
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAQR6 progestin and adipoQ receptor family member VI
PCDHB3 protocadherin beta 3
PDAP1 PDGFA associated protein 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
POFUT1 protein O-fucosyltransferase 1
PRDM1 PR domain containing 1, with ZNF domain
PRKX protein kinase, X-linked
PRSS21 protease, serine, 21 (testisin)
PSG4 pregnancy specific beta-1-glycoprotein 4
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB29 RAB29, member RAS oncogene family
RPL7 ribosomal protein L7
RPLP2 ribosomal protein, large, P2
SCAPER S-phase cyclin A-associated protein in the ER
SCN10A sodium channel, voltage gated, type X alpha subunit
SNAP23 synaptosomal-associated protein, 23kDa
SPDEF SAM pointed domain containing ETS transcription factor
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTBN1 spectrin, beta, non-erythrocytic 1
STRN3 striatin, calmodulin binding protein 3
STX1A syntaxin 1A (brain)
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM63A transmembrane protein 63A
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
UNC119 unc-119 homolog (C. elegans)
VASH1 vasohibin 1
WNK1 WNK lysine deficient protein kinase 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF304 zinc finger protein 304
ZYX zyxin

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
AHDC1 AT hook, DNA binding motif, containing 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
BCL9 B-cell CLL/lymphoma 9
BIRC7 baculoviral IAP repeat containing 7
BTBD2 BTB (POZ) domain containing 2
CASD1 CAS1 domain containing 1
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CES3 carboxylesterase 3
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYL1 crystallin, lambda 1
DCAF13 DDB1 and CUL4 associated factor 13
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELSPBP1 epididymal sperm binding protein 1
ERI3 ERI1 exoribonuclease family member 3
FAM189A2 family with sequence similarity 189, member A2
FAM63A family with sequence similarity 63, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FXR2 fragile X mental retardation, autosomal homolog 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HSPA2 heat shock 70kDa protein 2
IL15RA interleukin 15 receptor, alpha
INPPL1 inositol polyphosphate phosphatase-like 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD7 potassium channel tetramerization domain containing 7
KIAA0753 KIAA0753
LAMA3 laminin, alpha 3
LIN7B lin-7 homolog B (C. elegans)
LOC642236 FSHD region gene 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
LRP5 low density lipoprotein receptor-related protein 5
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBOAT2 membrane bound O-acyltransferase domain containing 2
MGC12488
MTERF4 mitochondrial transcription termination factor 4
NES nestin
NUPL2 nucleoporin like 2
ONECUT2 one cut homeobox 2
OTUD3 OTU deubiquitinase 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCBP4 poly(rC) binding protein 4
PCDHA9 protocadherin alpha 9
PGBD5 piggyBac transposable element derived 5
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHO1 pleckstrin homology domain containing, family O member 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTK6 protein tyrosine kinase 6
PUS1 pseudouridylate synthase 1
PYCRL pyrroline-5-carboxylate reductase-like
RAB23 RAB23, member RAS oncogene family
RASA2 RAS p21 protein activator 2
RCOR3 REST corepressor 3
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RFTN1 raftlin, lipid raft linker 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF25 ring finger protein 25
SAV1 salvador family WW domain containing protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIK1 salt-inducible kinase 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN1 tectonic family member 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM242 transmembrane protein 242
TMEM254 transmembrane protein 254
TMPRSS3 transmembrane protease, serine 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPAN1 tetraspanin 1
TUBG2 tubulin, gamma 2
UBL4A ubiquitin-like 4A
YIPF5 Yip1 domain family, member 5
ZC3H3 zinc finger CCCH-type containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX2 zinc finger homeobox 2
ZNF212 zinc finger protein 212
ZNF408 zinc finger protein 408
ZNF492 zinc finger protein 492
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696