Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the pyrantel-5513 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACO2 | aconitase 2, mitochondrial |
ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
ADRA1D | adrenoceptor alpha 1D |
AHI1 | Abelson helper integration site 1 |
AKAP8L | A kinase (PRKA) anchor protein 8-like |
ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
ANGEL2 | angel homolog 2 (Drosophila) |
ARMCX4 | armadillo repeat containing, X-linked 4 |
ATG13 | autophagy related 13 |
BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
C11ORF80 | chromosome 11 open reading frame 80 |
C14ORF1 | chromosome 14 open reading frame 1 |
CDKN2A | cyclin-dependent kinase inhibitor 2A |
CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
CLCN7 | chloride channel, voltage-sensitive 7 |
CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
COL1A1 | collagen, type I, alpha 1 |
COL8A2 | collagen, type VIII, alpha 2 |
CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
DNM3 | dynamin 3 |
FAM120C | family with sequence similarity 120C |
FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
FHL1 | four and a half LIM domains 1 |
FRMD1 | FERM domain containing 1 |
FXYD2 | FXYD domain containing ion transport regulator 2 |
GAS7 | growth arrest-specific 7 |
GMPR | guanosine monophosphate reductase |
GPR3 | G protein-coupled receptor 3 |
GRM2 | glutamate receptor, metabotropic 2 |
GRM8 | glutamate receptor, metabotropic 8 |
GSK3A | glycogen synthase kinase 3 alpha |
GTPBP1 | GTP binding protein 1 |
IFITM1 | interferon induced transmembrane protein 1 |
IGHA1 | immunoglobulin heavy constant alpha 1 |
IL24 | interleukin 24 |
IL36G | interleukin 36, gamma |
IRS2 | insulin receptor substrate 2 |
ITFG2 | integrin alpha FG-GAP repeat containing 2 |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
ITSN1 | intersectin 1 (SH3 domain protein) |
KLK2 | kallikrein-related peptidase 2 |
LAMB3 | laminin, beta 3 |
LIG4 | ligase IV, DNA, ATP-dependent |
LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
LMF2 | lipase maturation factor 2 |
MCTP1 | multiple C2 domains, transmembrane 1 |
MFAP3L | microfibrillar-associated protein 3-like |
MKL1 | megakaryoblastic leukemia (translocation) 1 |
MNDA | myeloid cell nuclear differentiation antigen |
MSR1 | macrophage scavenger receptor 1 |
MTRF1L | mitochondrial translational release factor 1-like |
MTSS1 | metastasis suppressor 1 |
NEFM | neurofilament, medium polypeptide |
NEIL1 | nei endonuclease VIII-like 1 (E. coli) |
NF1 | neurofibromin 1 |
NNAT | neuronatin |
NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
OCA2 | oculocutaneous albinism II |
OSMR | oncostatin M receptor |
PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
PAQR6 | progestin and adipoQ receptor family member VI |
PCDHB3 | protocadherin beta 3 |
PDAP1 | PDGFA associated protein 1 |
PHEX | phosphate regulating endopeptidase homolog, X-linked |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
POFUT1 | protein O-fucosyltransferase 1 |
PRDM1 | PR domain containing 1, with ZNF domain |
PRKX | protein kinase, X-linked |
PRSS21 | protease, serine, 21 (testisin) |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
PSG9 | pregnancy specific beta-1-glycoprotein 9 |
PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
RAB29 | RAB29, member RAS oncogene family |
RPL7 | ribosomal protein L7 |
RPLP2 | ribosomal protein, large, P2 |
SCAPER | S-phase cyclin A-associated protein in the ER |
SCN10A | sodium channel, voltage gated, type X alpha subunit |
SNAP23 | synaptosomal-associated protein, 23kDa |
SPDEF | SAM pointed domain containing ETS transcription factor |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
SPTBN1 | spectrin, beta, non-erythrocytic 1 |
STRN3 | striatin, calmodulin binding protein 3 |
STX1A | syntaxin 1A (brain) |
STX7 | syntaxin 7 |
SUGP1 | SURP and G patch domain containing 1 |
TICAM1 | toll-like receptor adaptor molecule 1 |
TMEM63A | transmembrane protein 63A |
TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
UNC119 | unc-119 homolog (C. elegans) |
VASH1 | vasohibin 1 |
WNK1 | WNK lysine deficient protein kinase 1 |
XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
ZNF304 | zinc finger protein 304 |
ZYX | zyxin |
Symbol | Name |
---|---|
ACOT8 | acyl-CoA thioesterase 8 |
AHDC1 | AT hook, DNA binding motif, containing 1 |
ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
BCL9 | B-cell CLL/lymphoma 9 |
BIRC7 | baculoviral IAP repeat containing 7 |
BTBD2 | BTB (POZ) domain containing 2 |
CASD1 | CAS1 domain containing 1 |
CASZ1 | castor zinc finger 1 |
CCDC85C | coiled-coil domain containing 85C |
CES3 | carboxylesterase 3 |
CNGB3 | cyclic nucleotide gated channel beta 3 |
CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
CRYL1 | crystallin, lambda 1 |
DCAF13 | DDB1 and CUL4 associated factor 13 |
DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
ELSPBP1 | epididymal sperm binding protein 1 |
ERI3 | ERI1 exoribonuclease family member 3 |
FAM189A2 | family with sequence similarity 189, member A2 |
FAM63A | family with sequence similarity 63, member A |
FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
FXR2 | fragile X mental retardation, autosomal homolog 2 |
GSTCD | glutathione S-transferase, C-terminal domain containing |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
HIST1H2AJ | histone cluster 1, H2aj |
HIST1H4D | histone cluster 1, H4d |
HSPA2 | heat shock 70kDa protein 2 |
IL15RA | interleukin 15 receptor, alpha |
INPPL1 | inositol polyphosphate phosphatase-like 1 |
KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
KCTD7 | potassium channel tetramerization domain containing 7 |
KIAA0753 | KIAA0753 |
LAMA3 | laminin, alpha 3 |
LIN7B | lin-7 homolog B (C. elegans) |
LOC642236 | FSHD region gene 1 pseudogene |
LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
LRP2 | low density lipoprotein receptor-related protein 2 |
LRP3 | low density lipoprotein receptor-related protein 3 |
LRP5 | low density lipoprotein receptor-related protein 5 |
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
MGC12488 | |
MTERF4 | mitochondrial transcription termination factor 4 |
NES | nestin |
NUPL2 | nucleoporin like 2 |
ONECUT2 | one cut homeobox 2 |
OTUD3 | OTU deubiquitinase 3 |
P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
PCBP4 | poly(rC) binding protein 4 |
PCDHA9 | protocadherin alpha 9 |
PGBD5 | piggyBac transposable element derived 5 |
PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
PTK6 | protein tyrosine kinase 6 |
PUS1 | pseudouridylate synthase 1 |
PYCRL | pyrroline-5-carboxylate reductase-like |
RAB23 | RAB23, member RAS oncogene family |
RASA2 | RAS p21 protein activator 2 |
RCOR3 | REST corepressor 3 |
RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
RFTN1 | raftlin, lipid raft linker 1 |
RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
RNF25 | ring finger protein 25 |
SAV1 | salvador family WW domain containing protein 1 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
SIK1 | salt-inducible kinase 1 |
SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
SMG9 | SMG9 nonsense mediated mRNA decay factor |
SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
TCTN1 | tectonic family member 1 |
THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
TMEM242 | transmembrane protein 242 |
TMEM254 | transmembrane protein 254 |
TMPRSS3 | transmembrane protease, serine 3 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
TSPAN1 | tetraspanin 1 |
TUBG2 | tubulin, gamma 2 |
UBL4A | ubiquitin-like 4A |
YIPF5 | Yip1 domain family, member 5 |
ZC3H3 | zinc finger CCCH-type containing 3 |
ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
ZFHX2 | zinc finger homeobox 2 |
ZNF212 | zinc finger protein 212 |
ZNF408 | zinc finger protein 408 |
ZNF492 | zinc finger protein 492 |
ZNF665 | zinc finger protein 665 |
ZNF675 | zinc finger protein 675 |
ZNF696 | zinc finger protein 696 |