pyrantel-pamoate Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

58 genes differentially expressed following the pyrantel-pamoate small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TIAM1 T-cell lymphoma invasion and metastasis 1 6.95923
FGFR4 fibroblast growth factor receptor 4 6.44479
TARBP1 TAR (HIV-1) RNA binding protein 1 5.92793
PLSCR3 phospholipid scramblase 3 4.10756
KREMEN2 kringle containing transmembrane protein 2 3.65529
TOR4A torsin family 4, member A 3.61778
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.61018
CD101 CD101 molecule 3.51927
ALPK3 alpha-kinase 3 3.47288
TSPAN4 tetraspanin 4 3.45589
PIMREG PICALM interacting mitotic regulator 3.44363
CD96 CD96 molecule 3.39056
TAAR3P trace amine associated receptor 3, pseudogene 3.38557
KSR1 kinase suppressor of ras 1 3.36244
TECTA tectorin alpha 3.36131
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.30227
TMEM132A transmembrane protein 132A 3.25321
PRORP protein only RNase P catalytic subunit 3.24792
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 3.22942
GSTZ1 glutathione S-transferase zeta 1 3.22606
RHOBTB1 Rho-related BTB domain containing 1 3.20851
RIPPLY3 ripply transcriptional repressor 3 3.17727
FANCG Fanconi anemia, complementation group G 3.17623
COTL1 coactosin-like F-actin binding protein 1 3.15232
ADGRE2 adhesion G protein-coupled receptor E2 3.15065
DRD3 dopamine receptor D3 3.11579
TLR8 toll-like receptor 8 3.11289
ARMCX4 armadillo repeat containing, X-linked 4 3.10994
TBXA2R thromboxane A2 receptor 3.06133
ANAPC15 anaphase promoting complex subunit 15 3.05827
MYO1C myosin IC 3.03934
ACTC1 actin, alpha, cardiac muscle 1 3.0274
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 3.02406
CUTA cutA divalent cation tolerance homolog (E. coli) 3.01663
CD320 CD320 molecule 3.00599

decreased expression

Symbol Name Standardized Value
MFSD6 major facilitator superfamily domain containing 6 -3.94534
CCN2 cellular communication network factor 2 -3.89152
SFRP4 secreted frizzled-related protein 4 -3.69462
CHIC2 cysteine-rich hydrophobic domain 2 -3.63498
FGB fibrinogen beta chain -3.48672
COL10A1 collagen, type X, alpha 1 -3.45737
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -3.42579
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -3.35251
MYD88 myeloid differentiation primary response 88 -3.26414
PPP1R13B protein phosphatase 1, regulatory subunit 13B -3.25188
ATXN3 ataxin 3 -3.24555
EXOC7 exocyst complex component 7 -3.21946
THBS2 thrombospondin 2 -3.21286
MIA3 melanoma inhibitory activity family, member 3 -3.19436
EGR2 early growth response 2 -3.17881
ITGB1BP1 integrin beta 1 binding protein 1 -3.13256
MYO1D myosin ID -3.09122
TRIM33 tripartite motif containing 33 -3.07951
PTGER4 prostaglandin E receptor 4 (subtype EP4) -3.04484
ARNT aryl hydrocarbon receptor nuclear translocator -3.02476
FIP1L1 factor interacting with PAPOLA and CPSF1 -3.01197
KDM3A lysine (K)-specific demethylase 3A -3.01079
SIRT3 sirtuin 3 -3.00772