| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the pyrazinamide-2478 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ACVR1B | activin A receptor, type IB |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| AIM1L | absent in melanoma 1-like |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANGPTL2 | angiopoietin-like 2 |
| AQP9 | aquaporin 9 |
| ATP10A | ATPase, class V, type 10A |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTD | biotinidase |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CLMN | calmin (calponin-like, transmembrane) |
| CNN1 | calponin 1, basic, smooth muscle |
| COL10A1 | collagen, type X, alpha 1 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| DAPK3 | death-associated protein kinase 3 |
| DCT | dopachrome tautomerase |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DENND5B | DENN/MADD domain containing 5B |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DNASE2B | deoxyribonuclease II beta |
| DUSP4 | dual specificity phosphatase 4 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| EVX1 | even-skipped homeobox 1 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FADS3 | fatty acid desaturase 3 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GLI3 | GLI family zinc finger 3 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPR22 | G protein-coupled receptor 22 |
| GPR35 | G protein-coupled receptor 35 |
| HBZ | hemoglobin, zeta |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXA11 | homeobox A11 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IHH | indian hedgehog |
| IL2RB | interleukin 2 receptor, beta |
| IL6ST | interleukin 6 signal transducer |
| INO80B | INO80 complex subunit B |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA1644 | KIAA1644 |
| KIF5C | kinesin family member 5C |
| KLHL35 | kelch-like family member 35 |
| LAG3 | lymphocyte-activation gene 3 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MAX | MYC associated factor X |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MXD4 | MAX dimerization protein 4 |
| MYBPH | myosin binding protein H |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPEPL1 | aminopeptidase-like 1 |
| OLAH | oleoyl-ACP hydrolase |
| OPRK1 | opioid receptor, kappa 1 |
| PLA2G16 | phospholipase A2, group XVI |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| RAB11B | RAB11B, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| REEP2 | receptor accessory protein 2 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RUFY3 | RUN and FYVE domain containing 3 |
| RUNDC3A | RUN domain containing 3A |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SFRP4 | secreted frizzled-related protein 4 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SPATA1 | spermatogenesis associated 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SSH3 | slingshot protein phosphatase 3 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYT12 | synaptotagmin XII |
| TAPBP | TAP binding protein (tapasin) |
| TAS2R4 | taste receptor, type 2, member 4 |
| TBC1D2 | TBC1 domain family, member 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM19 | transmembrane protein 19 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPAN9 | tetraspanin 9 |
| ULBP2 | UL16 binding protein 2 |
| USP12 | ubiquitin specific peptidase 12 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZNF365 | zinc finger protein 365 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALS2CL | ALS2 C-terminal like |
| ANXA2P2 | annexin A2 pseudogene 2 |
| AUP1 | ancient ubiquitous protein 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BSPRY | B-box and SPRY domain containing |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CCDC176 | coiled-coil domain containing 176 |
| CDC73 | cell division cycle 73 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CYB5R1 | cytochrome b5 reductase 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM3 | dynamin 3 |
| DOC2A | double C2-like domains, alpha |
| DOCK4 | dedicator of cytokinesis 4 |
| DPEP2 | dipeptidase 2 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FBXO31 | F-box protein 31 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FCHO1 | FCH domain only 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H2BE | histone cluster 1, H2be |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIAA1024 | KIAA1024 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100287590 | uncharacterized LOC100287590 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYRM1 | LYR motif containing 1 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEGF8 | multiple EGF-like-domains 8 |
| MRAS | muscle RAS oncogene homolog |
| MYO19 | myosin XIX |
| NDRG3 | NDRG family member 3 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| PCNP | PEST proteolytic signal containing nuclear protein |
| PITX2 | paired-like homeodomain 2 |
| PRKCZ | protein kinase C, zeta |
| PROCR | protein C receptor, endothelial |
| PYGB | phosphorylase, glycogen; brain |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD51AP1 | RAD51 associated protein 1 |
| RARS | arginyl-tRNA synthetase |
| RBM47 | RNA binding motif protein 47 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF31 | ring finger protein 31 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| SURF2 | surfeit 2 |
| TAOK1 | TAO kinase 1 |
| TCTN2 | tectonic family member 2 |
| TEC | tec protein tyrosine kinase |
| TET3 | tet methylcytosine dioxygenase 3 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TRIM16 | tripartite motif containing 16 |
| TRIM8 | tripartite motif containing 8 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| UPK3A | uroplakin 3A |
| USB1 | U6 snRNA biogenesis 1 |
| WDR60 | WD repeat domain 60 |
| WDR91 | WD repeat domain 91 |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF227 | zinc finger protein 227 |
| ZNF354A | zinc finger protein 354A |
| ZNF862 | zinc finger protein 862 |