pyrazinamide-2839 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pyrazinamide-2839 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRG1 adhesion G protein-coupled receptor G1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOC1 apolipoprotein C-I
ATF7IP activating transcription factor 7 interacting protein
BIN1 bridging integrator 1
C3ORF18 chromosome 3 open reading frame 18
C5AR2 complement component 5a receptor 2
C8ORF60 chromosome 8 open reading frame 60
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCDC71 coiled-coil domain containing 71
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD53 CD53 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CIZ1 CDKN1A interacting zinc finger protein 1
CLEC11A C-type lectin domain family 11, member A
CLSPN claspin
COL1A1 collagen, type I, alpha 1
CPNE7 copine VII
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYTH4 cytohesin 4
DIO2 deiodinase, iodothyronine, type II
DRD2 dopamine receptor D2
DTNB dystrobrevin, beta
EED embryonic ectoderm development
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ERN2 endoplasmic reticulum to nucleus signaling 2
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGFR1 fibroblast growth factor receptor 1
FLOT1 flotillin 1
FXYD5 FXYD domain containing ion transport regulator 5
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSN gelsolin
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIPK2 homeodomain interacting protein kinase 2
HIST1H4E histone cluster 1, H4e
HLA-C major histocompatibility complex, class I, C
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IL17RA interleukin 17 receptor A
IL6ST interleukin 6 signal transducer
ING2 inhibitor of growth family, member 2
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCTD7 potassium channel tetramerization domain containing 7
KDM8 lysine (K)-specific demethylase 8
LIMCH1 LIM and calponin homology domains 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MED1 mediator complex subunit 1
MFAP3L microfibrillar-associated protein 3-like
MITF microphthalmia-associated transcription factor
MST1 macrophage stimulating 1
MYO9A myosin IXA
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG2 NDRG family member 2
NOD1 nucleotide-binding oligomerization domain containing 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSUN6 NOP2/Sun domain family, member 6
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHGB5 protocadherin gamma subfamily B, 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PGAM2 phosphoglycerate mutase 2 (muscle)
PIGR polymeric immunoglobulin receptor
PLSCR1 phospholipid scramblase 1
PQLC2 PQ loop repeat containing 2
RAB11B RAB11B, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RBM5 RNA binding motif protein 5
RGS12 regulator of G-protein signaling 12
RHOBTB2 Rho-related BTB domain containing 2
RTCA RNA 3'-terminal phosphate cyclase
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLN sarcolipin
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOAT2 sterol O-acyltransferase 2
SOX15 SRY (sex determining region Y)-box 15
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSX1 synovial sarcoma, X breakpoint 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX7 syntaxin 7
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX6 T-box 6
TGM2 transglutaminase 2
UBE3A ubiquitin protein ligase E3A
ULK2 unc-51 like autophagy activating kinase 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WAPAL wings apart-like homolog (Drosophila)
ZNF236 zinc finger protein 236
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARC activity-regulated cytoskeleton-associated protein
BCL9 B-cell CLL/lymphoma 9
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF80 chromosome 11 open reading frame 80
C14ORF79 chromosome 14 open reading frame 79
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CLCF1 cardiotrophin-like cytokine factor 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
DSN1 DSN1, MIS12 kinetochore complex component
DTWD1 DTW domain containing 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERCC5 excision repair cross-complementation group 5
FBXL6 F-box and leucine-rich repeat protein 6
FCHSD2 FCH and double SH3 domains 2
FSD1 fibronectin type III and SPRY domain containing 1
GK3P glycerol kinase 3 pseudogene
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRAMD4 GRAM domain containing 4
GRWD1 glutamate-rich WD repeat containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HLA-J major histocompatibility complex, class I, J (pseudogene)
HP1BP3 heterochromatin protein 1, binding protein 3
HYI hydroxypyruvate isomerase (putative)
IL4R interleukin 4 receptor
IQCG IQ motif containing G
JMJD4 jumonji domain containing 4
KIAA0895 KIAA0895
KLK5 kallikrein-related peptidase 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOC100272216 uncharacterized LOC100272216
LOC390998 ribosomal protein L10 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC8E leucine rich repeat containing 8 family, member E
LYRM9 LYR motif containing 9
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MBNL3 muscleblind-like splicing regulator 3
MED9 mediator complex subunit 9
MPI mannose phosphate isomerase
MTMR11 myotubularin related protein 11
MYO1E myosin IE
NSD1 nuclear receptor binding SET domain protein 1
OLFML2A olfactomedin-like 2A
OLFML3 olfactomedin-like 3
P3H1 prolyl 3-hydroxylase 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIBF1 progesterone immunomodulatory binding factor 1
PLA2G15 phospholipase A2, group XV
PODXL2 podocalyxin-like 2
POLL polymerase (DNA directed), lambda
RAB33B RAB33B, member RAS oncogene family
RINT1 RAD50 interactor 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SIX1 SIX homeobox 1
SLC12A8 solute carrier family 12, member 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SPIDR scaffolding protein involved in DNA repair
SPON2 spondin 2, extracellular matrix protein
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STXBP2 syntaxin binding protein 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYBU syntabulin (syntaxin-interacting)
SYNC syncoilin, intermediate filament protein
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TGFB3 transforming growth factor, beta 3
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF204P zinc finger protein 204, pseudogene
ZNF329 zinc finger protein 329
ZNF623 zinc finger protein 623
ZNF767P zinc finger family member 767, pseudogene
ZNF770 zinc finger protein 770
ZNRD1-AS1 ZNRD1 antisense RNA 1