pyrazinamide-6617 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the pyrazinamide-6617 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANK2 ankyrin 2, neuronal
ANP32A-IT1 ANP32A intronic transcript 1
AQP7 aquaporin 7
ARHGAP44 Rho GTPase activating protein 44
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BCAS1 breast carcinoma amplified sequence 1
BTG2 BTG family, member 2
C17ORF59 chromosome 17 open reading frame 59
C8A complement component 8, alpha polypeptide
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL23 chemokine (C-C motif) ligand 23
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD82 CD82 molecule
CFH complement factor H
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLMN calmin (calponin-like, transmembrane)
CLPS colipase, pancreatic
COBL cordon-bleu WH2 repeat protein
COL1A2 collagen, type I, alpha 2
CTNS cystinosin, lysosomal cystine transporter
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DENND2A DENN/MADD domain containing 2A
DGCR8 DGCR8 microprocessor complex subunit
DKFZP434C153 DKFZP434C153 protein
DLX4 distal-less homeobox 4
DOCK5 dedicator of cytokinesis 5
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPF1 D4, zinc and double PHD fingers family 1
DUSP10 dual specificity phosphatase 10
DVL2 dishevelled segment polarity protein 2
ELAC1 elaC ribonuclease Z 1
EMP1 epithelial membrane protein 1
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
FER1L4 fer-1-like family member 4, pseudogene (functional)
FFAR2 free fatty acid receptor 2
FGF22 fibroblast growth factor 22
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GSK3A glycogen synthase kinase 3 alpha
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICOSLG inducible T-cell co-stimulator ligand
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLF3 Kruppel-like factor 3 (basic)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC390998 ribosomal protein L10 pseudogene
MAGEA5 melanoma antigen family A5
MAL mal, T-cell differentiation protein
METTL7A methyltransferase like 7A
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
N4BP2L1 NEDD4 binding protein 2-like 1
NDNF neuron-derived neurotrophic factor
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAPPA2 pappalysin 2
PARP6 poly (ADP-ribose) polymerase family, member 6
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLCH1 phospholipase C, eta 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPP5C protein phosphatase 5, catalytic subunit
PRKCQ protein kinase C, theta
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBMS2 RNA binding motif, single stranded interacting protein 2
SEC24A SEC24 family member A
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SOS2 son of sevenless homolog 2 (Drosophila)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TACR1 tachykinin receptor 1
THOC5 THO complex 5
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM180 transmembrane protein 180
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TSC22D2 TSC22 domain family, member 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UHRF1BP1L UHRF1 binding protein 1-like
ZBTB17 zinc finger and BTB domain containing 17
ZNF24 zinc finger protein 24
ZNF573 zinc finger protein 573
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACVR2B activin A receptor, type IIB
AFF4 AF4/FMR2 family, member 4
ALPK1 alpha-kinase 1
ANGPTL4 angiopoietin-like 4
ANXA2P3 annexin A2 pseudogene 3
APOLD1 apolipoprotein L domain containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAHCC1 BAH domain and coiled-coil containing 1
C11ORF30 chromosome 11 open reading frame 30
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNO cyclin O
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLDN1 claudin 1
CLSPN claspin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNN2 calponin 2
CPED1 cadherin-like and PC-esterase domain containing 1
CREB5 cAMP responsive element binding protein 5
CST6 cystatin E/M
CYBRD1 cytochrome b reductase 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DSPP dentin sialophosphoprotein
EHF ets homologous factor
ELP6 elongator acetyltransferase complex subunit 6
EMP3 epithelial membrane protein 3
ETNK2 ethanolamine kinase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM184A family with sequence similarity 184, member A
FBRS fibrosin
GALK1 galactokinase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GPR1 G protein-coupled receptor 1
HAMP hepcidin antimicrobial peptide
HIST1H3C histone cluster 1, H3c
HOXA4 homeobox A4
HOXC8 homeobox C8
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFT54 intraflagellar transport 54
IL11RA interleukin 11 receptor, alpha
IL2 interleukin 2
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
LAMC3 laminin, gamma 3
LRRK1 leucine-rich repeat kinase 1
LY96 lymphocyte antigen 96
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEF1 melanoma antigen family F1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFGE8 milk fat globule-EGF factor 8 protein
MGP matrix Gla protein
MOGS mannosyl-oligosaccharide glucosidase
MTMR11 myotubularin related protein 11
MUC3A mucin 3A, cell surface associated
NACA2 nascent polypeptide-associated complex alpha subunit 2
NME5 NME/NM23 family member 5
NR2C2 nuclear receptor subfamily 2, group C, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSR2 odd-skipped related transciption factor 2
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PID1 phosphotyrosine interaction domain containing 1
PLD3 phospholipase D family, member 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRB3 proline-rich protein BstNI subfamily 3
PRSS8 protease, serine, 8
R3HCC1L R3H domain and coiled-coil containing 1-like
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF39 ring finger protein 39
SAYSD1 SAYSVFN motif domain containing 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNORA21 small nucleolar RNA, H/ACA box 21
SPRYD7 SPRY domain containing 7
STARD3 StAR-related lipid transfer (START) domain containing 3
STON1 stonin 1
TMEM183A transmembrane protein 183A
TRAPPC6A trafficking protein particle complex 6A
TRIM21 tripartite motif containing 21
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBA3C tubulin, alpha 3c
USP19 ubiquitin specific peptidase 19
WDR18 WD repeat domain 18
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF358 zinc finger protein 358
ZNF667 zinc finger protein 667