| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pyridoxine-1759 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APP | amyloid beta (A4) precursor protein |
| ARG1 | arginase 1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARRB2 | arrestin, beta 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| C1ORF50 | chromosome 1 open reading frame 50 |
| C21ORF33 | chromosome 21 open reading frame 33 |
| CACYBP | calcyclin binding protein |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CIAO1 | cytosolic iron-sulfur assembly component 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOPEY1 | dopey family member 1 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EGR2 | early growth response 2 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ELMO2 | engulfment and cell motility 2 |
| ENAH | enabled homolog (Drosophila) |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPS8L1 | EPS8-like 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO46 | F-box protein 46 |
| FN1 | fibronectin 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GDF5 | growth differentiation factor 5 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 |
| HP | haptoglobin |
| HRASLS2 | HRAS-like suppressor 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KIAA0226 | KIAA0226 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MAGED2 | melanoma antigen family D2 |
| MAP1S | microtubule-associated protein 1S |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MED12 | mediator complex subunit 12 |
| MED7 | mediator complex subunit 7 |
| MPHOSPH9 | M-phase phosphoprotein 9 |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP1 | NEDD4 binding protein 1 |
| NDRG2 | NDRG family member 2 |
| NPPA | natriuretic peptide A |
| NUP62 | nucleoporin 62kDa |
| ORC4 | origin recognition complex, subunit 4 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PISD | phosphatidylserine decarboxylase |
| PLD2 | phospholipase D2 |
| PODNL1 | podocan-like 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| PRDM4 | PR domain containing 4 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAD17 | RAD17 homolog (S. pombe) |
| RBM10 | RNA binding motif protein 10 |
| RBM14 | RNA binding motif protein 14 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RNF123 | ring finger protein 123 |
| RRBP1 | ribosome binding protein 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| RUNX3 | runt-related transcription factor 3 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SHPK | sedoheptulokinase |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLK | STE20-like kinase |
| SOAT1 | sterol O-acyltransferase 1 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| STX1A | syntaxin 1A (brain) |
| SUMO1 | small ubiquitin-like modifier 1 |
| TMEM80 | transmembrane protein 80 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TUBA4B | tubulin, alpha 4b |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBE3A | ubiquitin protein ligase E3A |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WDR60 | WD repeat domain 60 |
| WIPF2 | WAS/WASL interacting protein family, member 2 |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 |
| ASL | argininosuccinate lyase |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BBC3 | BCL2 binding component 3 |
| CARD9 | caspase recruitment domain family, member 9 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC47 | coiled-coil domain containing 47 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CSAD | cysteine sulfinic acid decarboxylase |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DUSP12 | dual specificity phosphatase 12 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERCC3 | excision repair cross-complementation group 3 |
| FAM188A | family with sequence similarity 188, member A |
| FAM50B | family with sequence similarity 50, member B |
| FANCE | Fanconi anemia, complementation group E |
| FMO4 | flavin containing monooxygenase 4 |
| FOXK2 | forkhead box K2 |
| FPGS | folylpolyglutamate synthase |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSR | glutathione reductase |
| GTF2I | general transcription factor IIi |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HIST1H4C | histone cluster 1, H4c |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOMER1 | homer scaffolding protein 1 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF18A | kinesin family member 18A |
| KIFAP3 | kinesin-associated protein 3 |
| KIFC1 | kinesin family member C1 |
| KLHL12 | kelch-like family member 12 |
| KRT38 | keratin 38, type I |
| LIG1 | ligase I, DNA, ATP-dependent |
| LOC729164 | hCG1732469 |
| MED17 | mediator complex subunit 17 |
| MLYCD | malonyl-CoA decarboxylase |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NMD3 | NMD3 ribosome export adaptor |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUP93 | nucleoporin 93kDa |
| ORC2 | origin recognition complex, subunit 2 |
| PANX1 | pannexin 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARPBP | PARP1 binding protein |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLIN3 | perilipin 3 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKX | protein kinase, X-linked |
| PTH2R | parathyroid hormone 2 receptor |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RANGAP1 | Ran GTPase activating protein 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPL39L | ribosomal protein L39-like |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SIRT6 | sirtuin 6 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| STAC | SH3 and cysteine rich domain |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TMEM14A | transmembrane protein 14A |
| TMEM214 | transmembrane protein 214 |
| TMEM230 | transmembrane protein 230 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRIM25 | tripartite motif containing 25 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WDR13 | WD repeat domain 13 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF432 | zinc finger protein 432 |
| ZNF529 | zinc finger protein 529 |
