pyridoxine-2751 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the pyridoxine-2751 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AKAP8L A kinase (PRKA) anchor protein 8-like
ALOX5 arachidonate 5-lipoxygenase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BBS9 Bardet-Biedl syndrome 9
C1ORF95 chromosome 1 open reading frame 95
C22ORF46 chromosome 22 open reading frame 46
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDON cell adhesion associated, oncogene regulated
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CNTN1 contactin 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRY2 cryptochrome circadian clock 2
CTSZ cathepsin Z
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DENND5B DENN/MADD domain containing 5B
FADS2 fatty acid desaturase 2
FAM212B family with sequence similarity 212, member B
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FBXO41 F-box protein 41
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAMT guanidinoacetate N-methyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GGT1 gamma-glutamyltransferase 1
GPM6A glycoprotein M6A
GREB1L growth regulation by estrogen in breast cancer-like
GRM1 glutamate receptor, metabotropic 1
GSK3A glycogen synthase kinase 3 alpha
HFE hemochromatosis
HIPK2 homeodomain interacting protein kinase 2
HIST1H1D histone cluster 1, H1d
HIST2H2AA3 histone cluster 2, H2aa3
HLA-C major histocompatibility complex, class I, C
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IL10RA interleukin 10 receptor, alpha
IL2RG interleukin 2 receptor, gamma
INHBE inhibin, beta E
INO80D INO80 complex subunit D
IQCK IQ motif containing K
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIAA0319L KIAA0319-like
LTBP4 latent transforming growth factor beta binding protein 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MEF2D myocyte enhancer factor 2D
MON2 MON2 homolog (S. cerevisiae)
NOL4 nucleolar protein 4
PCDHB12 protocadherin beta 12
PCSK6 proprotein convertase subtilisin/kexin type 6
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRF1 perforin 1 (pore forming protein)
PRKCE protein kinase C, epsilon
PXN paxillin
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
RSG1 REM2 and RAB-like small GTPase 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SH2B1 SH2B adaptor protein 1
SH2D3A SH2 domain containing 3A
SH3GL3 SH3-domain GRB2-like 3
SH3PXD2A SH3 and PX domains 2A
SIX2 SIX homeobox 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SPAG8 sperm associated antigen 8
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STARD3 StAR-related lipid transfer (START) domain containing 3
SYN3 synapsin III
SYNJ2 synaptojanin 2
TAOK2 TAO kinase 2
TBXA2R thromboxane A2 receptor
TCF3 transcription factor 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLDC1 TBC/LysM-associated domain containing 1
TM4SF1 transmembrane 4 L six family member 1
TMEM53 transmembrane protein 53
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNS2 tensin 2
TPMT thiopurine S-methyltransferase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VN1R1 vomeronasal 1 receptor 1
WNT16 wingless-type MMTV integration site family, member 16
XDH xanthine dehydrogenase
ZDHHC14 zinc finger, DHHC-type containing 14
ZER1 zyg-11 related, cell cycle regulator
ZFAND5 zinc finger, AN1-type domain 5
ZNF230 zinc finger protein 230
ZNF304 zinc finger protein 304

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADM adrenomedullin
AMDHD2 amidohydrolase domain containing 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
CBX7 chromobox homolog 7
CCDC92 coiled-coil domain containing 92
CCNO cyclin O
CDK5 cyclin-dependent kinase 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHKB choline kinase beta
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAAF2 dynein, axonemal, assembly factor 2
DPF2 D4, zinc and double PHD fingers family 2
EFNA3 ephrin-A3
EFNA4 ephrin-A4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA2 EYA transcriptional coactivator and phosphatase 2
F8 coagulation factor VIII, procoagulant component
FAM188A family with sequence similarity 188, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GNPDA1 glucosamine-6-phosphate deaminase 1
GPATCH3 G patch domain containing 3
GPR143 G protein-coupled receptor 143
H1F0 H1 histone family, member 0
HIST1H2AL histone cluster 1, H2al
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IL17RA interleukin 17 receptor A
IL22 interleukin 22
INF2 inverted formin, FH2 and WH2 domain containing
ITPKB inositol-trisphosphate 3-kinase B
KDM7A lysine (K)-specific demethylase 7A
LHX6 LIM homeobox 6
LRP3 low density lipoprotein receptor-related protein 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MTCP1 mature T-cell proliferation 1
MTERF1 mitochondrial transcription termination factor 1
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYBBP1A MYB binding protein (P160) 1a
NCALD neurocalcin delta
NIPAL2 NIPA-like domain containing 2
PARD6A par-6 family cell polarity regulator alpha
PCDHA9 protocadherin alpha 9
PCDHB8 protocadherin beta 8
PHGDH phosphoglycerate dehydrogenase
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD2 phospholipase D2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB8B RAB8B, member RAS oncogene family
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF43 ring finger protein 43
RPAP2 RNA polymerase II associated protein 2
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD1A SET domain containing 1A
SHARPIN SHANK-associated RH domain interactor
SIRAL2 SIR2 antiphage like 2
SIX1 SIX homeobox 1
SLC12A9 solute carrier family 12, member 9
SLC35F6 solute carrier family 35, member F6
SLC46A3 solute carrier family 46, member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMAD7 SMAD family member 7
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SSBP3 single stranded DNA binding protein 3
STBD1 starch binding domain 1
STRN striatin, calmodulin binding protein
SYT17 synaptotagmin XVII
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
TSPYL2 TSPY-like 2
VGF VGF nerve growth factor inducible
WDR13 WD repeat domain 13
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF282 zinc finger protein 282
ZNF324 zinc finger protein 324
ZNF862 zinc finger protein 862