pyridoxine-5813 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the pyridoxine-5813 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
AIM2 absent in melanoma 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPT4 angiopoietin 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ASB1 ankyrin repeat and SOCS box containing 1
ATP10A ATPase, class V, type 10A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
CD82 CD82 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
COPE coatomer protein complex, subunit epsilon
CORO2A coronin, actin binding protein, 2A
DBF4B DBF4 zinc finger B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DESI2 desumoylating isopeptidase 2
DPF3 D4, zinc and double PHD fingers, family 3
EDN1 endothelin 1
EPHA5 EPH receptor A5
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
FAM50B family with sequence similarity 50, member B
FGFR1 fibroblast growth factor receptor 1
FLJ11292
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLG1 golgi glycoprotein 1
GRIP2 glutamate receptor interacting protein 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC7 histone deacetylase 7
HIC2 hypermethylated in cancer 2
HOOK1 hook microtubule-tethering protein 1
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IQCK IQ motif containing K
IRAK4 interleukin-1 receptor-associated kinase 4
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD13 potassium channel tetramerization domain containing 13
KRT6B keratin 6B, type II
KRT75 keratin 75, type II
LHX1 LIM homeobox 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMCD1 LIM and cysteine-rich domains 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MANBA mannosidase, beta A, lysosomal
MKL1 megakaryoblastic leukemia (translocation) 1
MTAP methylthioadenosine phosphorylase
MTMR7 myotubularin related protein 7
MXD3 MAX dimerization protein 3
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NID2 nidogen 2 (osteonidogen)
NMBR neuromedin B receptor
NOTCH4 notch 4
OSBPL10 oxysterol binding protein-like 10
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PID1 phosphotyrosine interaction domain containing 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PNMA2 paraneoplastic Ma antigen 2
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRDX2 peroxiredoxin 2
PRF1 perforin 1 (pore forming protein)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SAMD4A sterile alpha motif domain containing 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SIX3 SIX homeobox 3
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC43A3 solute carrier family 43, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNRK SNF related kinase
SOS2 son of sevenless homolog 2 (Drosophila)
SRP72 signal recognition particle 72kDa
STAB2 stabilin 2
STX2 syntaxin 2
TAOK2 TAO kinase 2
TBX10 T-box 10
TEF thyrotrophic embryonic factor
TESPA1 thymocyte expressed, positive selection associated 1
TFIP11 tuftelin interacting protein 11
TMCC1 transmembrane and coiled-coil domain family 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPR translocated promoter region, nuclear basket protein
TRIM2 tripartite motif containing 2
TRIM62 tripartite motif containing 62
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP46 ubiquitin specific peptidase 46
VAV2 vav 2 guanine nucleotide exchange factor
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
YY1 YY1 transcription factor
ZBTB17 zinc finger and BTB domain containing 17
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACP2 acid phosphatase 2, lysosomal
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANAPC2 anaphase promoting complex subunit 2
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATF7IP2 activating transcription factor 7 interacting protein 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIRC3 baculoviral IAP repeat containing 3
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF63 chromosome 11 open reading frame 63
C18ORF8 chromosome 18 open reading frame 8
C1ORF56 chromosome 1 open reading frame 56
C21ORF91 chromosome 21 open reading frame 91
CHRM3 cholinergic receptor, muscarinic 3
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCN5 chloride channel, voltage-sensitive 5
COBL cordon-bleu WH2 repeat protein
CTSD cathepsin D
CXCL3 chemokine (C-X-C motif) ligand 3
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF17 DDB1 and CUL4 associated factor 17
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EGF epidermal growth factor
EN2 engrailed homeobox 2
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM206A family with sequence similarity 206, member A
FSD1 fibronectin type III and SPRY domain containing 1
GMIP GEM interacting protein
HELZ helicase with zinc finger
HIST1H2AM histone cluster 1, H2am
IFT54 intraflagellar transport 54
ITPKB inositol-trisphosphate 3-kinase B
KIAA0754 KIAA0754
KIFAP3 kinesin-associated protein 3
KLHL12 kelch-like family member 12
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LPAR6 lysophosphatidic acid receptor 6
LRRC16A leucine rich repeat containing 16A
LRRK1 leucine-rich repeat kinase 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP6D1 MAP6 domain containing 1
MBIP MAP3K12 binding inhibitory protein 1
MITF microphthalmia-associated transcription factor
MKS1 Meckel syndrome, type 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MYO19 myosin XIX
NHEJ1 nonhomologous end-joining factor 1
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR6 progestin and adipoQ receptor family member VI
PCID2 PCI domain containing 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PXDC1 PX domain containing 1
RAB33B RAB33B, member RAS oncogene family
RANBP17 RAN binding protein 17
RARS arginyl-tRNA synthetase
RNF121 ring finger protein 121
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP2 RNA polymerase II associated protein 2
RUSC2 RUN and SH3 domain containing 2
SCYL2 SCY1-like 2 (S. cerevisiae)
SLC35G2 solute carrier family 35, member G2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SPAG4 sperm associated antigen 4
STX17 syntaxin 17
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX19 T-box 19
TGFB3 transforming growth factor, beta 3
TGS1 trimethylguanosine synthase 1
TMCC2 transmembrane and coiled-coil domain family 2
TMEM212 transmembrane protein 212
TNK1 tyrosine kinase, non-receptor, 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR37 WD repeat domain 37
WDR91 WD repeat domain 91
XAB2 XPA binding protein 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZMYM1 zinc finger, MYM-type 1
ZNF34 zinc finger protein 34
ZNF8 zinc finger protein 8
ZSCAN31 zinc finger and SCAN domain containing 31