| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the pyridoxine-7171 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AMACR | alpha-methylacyl-CoA racemase |
| APOM | apolipoprotein M |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATP11A | ATPase, class VI, type 11A |
| BMP1 | bone morphogenetic protein 1 |
| CAPN10 | calpain 10 |
| CBX8 | chromobox homolog 8 |
| CDK20 | cyclin-dependent kinase 20 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CES3 | carboxylesterase 3 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCTN1 | dynactin 1 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DESI2 | desumoylating isopeptidase 2 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DTNA | dystrobrevin, alpha |
| EML1 | echinoderm microtubule associated protein like 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERP44 | endoplasmic reticulum protein 44 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FDPS | farnesyl diphosphate synthase |
| GPR157 | G protein-coupled receptor 157 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HDAC4 | histone deacetylase 4 |
| HIST1H4E | histone cluster 1, H4e |
| HIST1H4F | histone cluster 1, H4f |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC4 | homeobox C4 |
| HRK | harakiri, BCL2 interacting protein |
| IFT140 | intraflagellar transport 140 |
| INE1 | inactivation escape 1 (non-protein coding) |
| IPO8 | importin 8 |
| JUN | jun proto-oncogene |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MEFV | Mediterranean fever |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MID2 | midline 2 |
| MTSS1L | metastasis suppressor 1-like |
| MYO9B | myosin IXB |
| NEB | nebulin |
| PCDH9 | protocadherin 9 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHF20 | PHD finger protein 20 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRPH | peripherin |
| PSAT1 | phosphoserine aminotransferase 1 |
| RNF122 | ring finger protein 122 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL13 | ribosomal protein L13 |
| RPL18 | ribosomal protein L18 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SAFB2 | scaffold attachment factor B2 |
| SGSM3 | small G protein signaling modulator 3 |
| SH3BP1 | SH3-domain binding protein 1 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMAD3 | SMAD family member 3 |
| SMC1A | structural maintenance of chromosomes 1A |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SP100 | SP100 nuclear antigen |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRRT | serrate, RNA effector molecule |
| STRN3 | striatin, calmodulin binding protein 3 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TEP1 | telomerase-associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM254 | transmembrane protein 254 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| YIPF4 | Yip1 domain family, member 4 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF473 | zinc finger protein 473 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BCORL1 | BCL6 corepressor-like 1 |
| BEX4 | brain expressed, X-linked 4 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BTBD2 | BTB (POZ) domain containing 2 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CAPN15 | calpain 15 |
| CBR4 | carbonyl reductase 4 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNT1 | cyclin T1 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHMP6 | charged multivesicular body protein 6 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CIC | capicua transcriptional repressor |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CSNK1E | casein kinase 1, epsilon |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNMBP | dynamin binding protein |
| DUSP8 | dual specificity phosphatase 8 |
| ELMO3 | engulfment and cell motility 3 |
| EPHA2 | EPH receptor A2 |
| FAM188A | family with sequence similarity 188, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FZD4 | frizzled class receptor 4 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR87 | G protein-coupled receptor 87 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HINFP | histone H4 transcription factor |
| ING3 | inhibitor of growth family, member 3 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRRC42 | leucine rich repeat containing 42 |
| MAP9 | microtubule-associated protein 9 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| METTL4 | methyltransferase like 4 |
| MON1B | MON1 secretory trafficking family member B |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTCL1 | microtubule crosslinking factor 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLCG1 | phospholipase C, gamma 1 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPAN | peter pan homolog (Drosophila) |
| PYGB | phosphorylase, glycogen; brain |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB5B | RAB5B, member RAS oncogene family |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF31 | ring finger protein 31 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SALL2 | spalt-like transcription factor 2 |
| SAV1 | salvador family WW domain containing protein 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SMAD7 | SMAD family member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMYD5 | SMYD family member 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNGR3 | synaptogyrin 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D12 | TBC1 domain family, member 12 |
| TNRC6B | trinucleotide repeat containing 6B |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TTC31 | tetratricopeptide repeat domain 31 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP6 | ubiquitin specific peptidase 6 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VGF | VGF nerve growth factor inducible |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR60 | WD repeat domain 60 |
| XAB2 | XPA binding protein 2 |
| YEATS2 | YEATS domain containing 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| ZNF276 | zinc finger protein 276 |