pyridoxine Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. (Chemical Entities of Biological Interest Ontology, CHEBI_16709)
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Genes

6 genes differentially expressed following the pyridoxine small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
NPTXR neuronal pentraxin receptor 3.46116
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 3.14227

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.02865
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -3.95474
TLK2 tousled-like kinase 2 -3.61371
HEATR6 HEAT repeat containing 6 -3.10753