| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pyrimethamine-1474 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| BCL2A1 | BCL2-related protein A1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCPG1 | cell cycle progression 1 |
| CD44 | CD44 molecule (Indian blood group) |
| CD6 | CD6 molecule |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CUL9 | cullin 9 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DCTN1 | dynactin 1 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| FAM134B | family with sequence similarity 134, member B |
| FBLN1 | fibulin 1 |
| FGF16 | fibroblast growth factor 16 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAS2 | growth arrest-specific 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFI1 | growth factor independent 1 transcription repressor |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GYG2 | glycogenin 2 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HN1L | hematological and neurological expressed 1-like |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 |
| HOXC8 | homeobox C8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IQCG | IQ motif containing G |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KRT31 | keratin 31, type I |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LHX1 | LIM homeobox 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC23 | leucine rich repeat containing 23 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP25 | matrix metallopeptidase 25 |
| NELL2 | NEL-like 2 (chicken) |
| NF2 | neurofibromin 2 (merlin) |
| NUP214 | nucleoporin 214kDa |
| PCBP3 | poly(rC) binding protein 3 |
| PCDHB6 | protocadherin beta 6 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PON1 | paraoxonase 1 |
| POU3F4 | POU class 3 homeobox 4 |
| PRDX2 | peroxiredoxin 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB6A | RAB6A, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RECQL5 | RecQ protein-like 5 |
| RHEB | Ras homolog enriched in brain |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SCD5 | stearoyl-CoA desaturase 5 |
| SETD1A | SET domain containing 1A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPON1 | spondin 1, extracellular matrix protein |
| TAOK1 | TAO kinase 1 |
| TBC1D2B | TBC1 domain family, member 2B |
| TLR2 | toll-like receptor 2 |
| TMEM144 | transmembrane protein 144 |
| TMEM209 | transmembrane protein 209 |
| TMEM259 | transmembrane protein 259 |
| TMPRSS2 | transmembrane protease, serine 2 |
| UBE3A | ubiquitin protein ligase E3A |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF134 | zinc finger protein 134 |
| Symbol | Name |
|---|---|
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARSB | arylsulfatase B |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AZI2 | 5-azacytidine induced 2 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPRIN2 | caprin family member 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC92 | coiled-coil domain containing 92 |
| CCNT1 | cyclin T1 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CIDEC | cell death-inducing DFFA-like effector c |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CUEDC1 | CUE domain containing 1 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DOC2A | double C2-like domains, alpha |
| EPHA2 | EPH receptor A2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO3 | F-box protein 3 |
| FBXO31 | F-box protein 31 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GID4 | GID complex subunit 4 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HINFP | histone H4 transcription factor |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IPO8 | importin 8 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| MXD3 | MAX dimerization protein 3 |
| NAV2 | neuron navigator 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OLFML2A | olfactomedin-like 2A |
| PARD6A | par-6 family cell polarity regulator alpha |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNF121 | ring finger protein 121 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19B | ring finger protein 19B |
| RNF31 | ring finger protein 31 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNX15 | sorting nexin 15 |
| SNX16 | sorting nexin 16 |
| SYNGR3 | synaptogyrin 3 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TMEM104 | transmembrane protein 104 |
| TMEM184B | transmembrane protein 184B |
| TMEM53 | transmembrane protein 53 |
| TMSB15A | thymosin beta 15a |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAIP | TRAF interacting protein |
| TSPYL2 | TSPY-like 2 |
| UBQLN4 | ubiquilin 4 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR25 | WD repeat domain 25 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF423 | zinc finger protein 423 |
| ZNF573 | zinc finger protein 573 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
