| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pyrimethamine-1894 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADK | adenosine kinase |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANKRD12 | ankyrin repeat domain 12 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AXIN1 | axin 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BMP1 | bone morphogenetic protein 1 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| CDK19 | cyclin-dependent kinase 19 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CSNK1E | casein kinase 1, epsilon |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUS2 | dihydrouridine synthase 2 |
| EGR1 | early growth response 1 |
| ELK1 | ELK1, member of ETS oncogene family |
| EP300 | E1A binding protein p300 |
| FAM188A | family with sequence similarity 188, member A |
| FAM63A | family with sequence similarity 63, member A |
| GLG1 | golgi glycoprotein 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GRM6 | glutamate receptor, metabotropic 6 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HFE | hemochromatosis |
| ICAM1 | intercellular adhesion molecule 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA1109 | KIAA1109 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLHL3 | kelch-like family member 3 |
| KPTN | kaptin (actin binding protein) |
| LOC647070 | uncharacterized LOC647070 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LUZP4 | leucine zipper protein 4 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP1S | microtubule-associated protein 1S |
| MAP7 | microtubule-associated protein 7 |
| MTMR11 | myotubularin related protein 11 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MVK | mevalonate kinase |
| NADK | NAD kinase |
| NHLRC2 | NHL repeat containing 2 |
| NXPH3 | neurexophilin 3 |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PGC | progastricsin (pepsinogen C) |
| PHKB | phosphorylase kinase, beta |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PROCR | protein C receptor, endothelial |
| PRR5 | proline rich 5 (renal) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RHOQ | ras homolog family member Q |
| RIOK3 | RIO kinase 3 |
| SH2D1A | SH2 domain containing 1A |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIRT3 | sirtuin 3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SPRR1A | small proline-rich protein 1A |
| SRPK3 | SRSF protein kinase 3 |
| SSBP2 | single-stranded DNA binding protein 2 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM74B | transmembrane protein 74B |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM45 | tripartite motif containing 45 |
| UPK1B | uroplakin 1B |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP34 | ubiquitin specific peptidase 34 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| VSNL1 | visinin-like 1 |
| WDR62 | WD repeat domain 62 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF710 | zinc finger protein 710 |
| ZNF721 | zinc finger protein 721 |
| Symbol | Name |
|---|---|
| AAMP | angio-associated, migratory cell protein |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AKTIP | AKT interacting protein |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| AURKAIP1 | aurora kinase A interacting protein 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BYSL | bystin-like |
| C21ORF59 | chromosome 21 open reading frame 59 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC130 | coiled-coil domain containing 130 |
| CD151 | CD151 molecule (Raph blood group) |
| CDCA3 | cell division cycle associated 3 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CTSF | cathepsin F |
| DPP3 | dipeptidyl-peptidase 3 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| EMC9 | ER membrane protein complex subunit 9 |
| ERCC2 | excision repair cross-complementation group 2 |
| EXOC5 | exocyst complex component 5 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FXN | frataxin |
| FZD2 | frizzled class receptor 2 |
| GCC2 | GRIP and coiled-coil domain containing 2 |
| GPATCH1 | G patch domain containing 1 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HELLS | helicase, lymphoid-specific |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BI | histone cluster 1, H2bi |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOOK2 | hook microtubule-tethering protein 2 |
| HOXB13 | homeobox B13 |
| HRSP12 | heat-responsive protein 12 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| INTS12 | integrator complex subunit 12 |
| KIF18A | kinesin family member 18A |
| KIN | Kin17 DNA and RNA binding protein |
| KRT34 | keratin 34, type I |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MRPL40 | mitochondrial ribosomal protein L40 |
| MT1HL1 | metallothionein 1H-like 1 |
| NADSYN1 | NAD synthetase 1 |
| NINJ1 | ninjurin 1 |
| NMD3 | NMD3 ribosome export adaptor |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OSGEP | O-sialoglycoprotein endopeptidase |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| PUS1 | pseudouridylate synthase 1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RIC8A | RIC8 guanine nucleotide exchange factor A |
| RTCB | RNA 2',3'-cyclic phosphate and 5'-OH ligase |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCRN1 | secernin 1 |
| SECTM1 | secreted and transmembrane 1 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SIX1 | SIX homeobox 1 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| SURF2 | surfeit 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM110 | transmembrane protein 110 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRIM58 | tripartite motif containing 58 |
| TSG101 | tumor susceptibility 101 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UBAC1 | UBA domain containing 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF696 | zinc finger protein 696 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
