| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pyrimethamine-1974 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ACTN4 | actinin, alpha 4 |
| AES | amino-terminal enhancer of split |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CCDC25 | coiled-coil domain containing 25 |
| CCND1 | cyclin D1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP68 | centrosomal protein 68kDa |
| CPOX | coproporphyrinogen oxidase |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CTSZ | cathepsin Z |
| DAPK1 | death-associated protein kinase 1 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DUSP2 | dual specificity phosphatase 2 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM172A | family with sequence similarity 172, member A |
| FAM3C | family with sequence similarity 3, member C |
| FBXL5 | F-box and leucine-rich repeat protein 5 |
| FDX1 | ferredoxin 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| GAB2 | GRB2-associated binding protein 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GCFC2 | GC-rich sequence DNA-binding factor 2 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GRM6 | glutamate receptor, metabotropic 6 |
| GSAP | gamma-secretase activating protein |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIRA | histone cell cycle regulator |
| HMGN4 | high mobility group nucleosomal binding domain 4 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL1RAP | interleukin 1 receptor accessory protein |
| IVNS1ABP | influenza virus NS1A binding protein |
| JAG1 | jagged 1 |
| KLHDC8A | kelch domain containing 8A |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LYRM1 | LYR motif containing 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTMR2 | myotubularin related protein 2 |
| MX1 | MX dynamin-like GTPase 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDS5A | PDS5 cohesin associated factor A |
| PGAP2 | post-GPI attachment to proteins 2 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLA2G12A | phospholipase A2, group XIIA |
| PLCD1 | phospholipase C, delta 1 |
| PLCG1 | phospholipase C, gamma 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB7A | RAB7A, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RMDN1 | regulator of microtubule dynamics 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCLY | selenocysteine lyase |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETD6 | SET domain containing 6 |
| SGSM2 | small G protein signaling modulator 2 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC38A6 | solute carrier family 38, member 6 |
| SMC5 | structural maintenance of chromosomes 5 |
| STX6 | syntaxin 6 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| THEM6 | thioesterase superfamily member 6 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM97 | transmembrane protein 97 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRD | T cell receptor delta locus |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TRPV5 | transient receptor potential cation channel, subfamily V, member 5 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZFYVE26 | zinc finger, FYVE domain containing 26 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF451 | zinc finger protein 451 |
| ZNF529 | zinc finger protein 529 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| AAMP | angio-associated, migratory cell protein |
| ACP2 | acid phosphatase 2, lysosomal |
| AKIRIN1 | akirin 1 |
| ALPK1 | alpha-kinase 1 |
| ANXA6 | annexin A6 |
| ARHGAP19 | Rho GTPase activating protein 19 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| BCL7C | B-cell CLL/lymphoma 7C |
| BIN2 | bridging integrator 2 |
| BPI | bactericidal/permeability-increasing protein |
| BRD9 | bromodomain containing 9 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| BTNL3 | butyrophilin-like 3 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C3 | complement component 3 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC47 | coiled-coil domain containing 47 |
| CCNB1 | cyclin B1 |
| CCNT1 | cyclin T1 |
| CDC20 | cell division cycle 20 |
| CENPE | centromere protein E, 312kDa |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
| CMTR1 | cap methyltransferase 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEPDC1 | DEP domain containing 1 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DGKZ | diacylglycerol kinase, zeta |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERF | Ets2 repressor factor |
| FKBP2 | FK506 binding protein 2, 13kDa |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| H1FX | H1 histone family, member X |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4C | histone cluster 1, H4c |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F |
| INO80D | INO80 complex subunit D |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF20A | kinesin family member 20A |
| KIF4A | kinesin family member 4A |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MLPH | melanophilin |
| MYDGF | myeloid-derived growth factor |
| NARF | nuclear prelamin A recognition factor |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NEK11 | NIMA-related kinase 11 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NT5DC2 | 5'-nucleotidase domain containing 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PLK1 | polo-like kinase 1 |
| PRMT1 | protein arginine methyltransferase 1 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| RBM4B | RNA binding motif protein 4B |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNASE6 | ribonuclease, RNase A family, k6 |
| RNF4 | ring finger protein 4 |
| SETD1B | SET domain containing 1B |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SP140L | SP140 nuclear body protein-like |
| SPI1 | Spi-1 proto-oncogene |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| STAC | SH3 and cysteine rich domain |
| TAC3 | tachykinin 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TPX2 | TPX2, microtubule-associated |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UNC13B | unc-13 homolog B (C. elegans) |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VASP | vasodilator-stimulated phosphoprotein |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
