| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pyrimethamine-4779 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARL4C | ADP-ribosylation factor-like 4C |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CDC14A | cell division cycle 14A |
| CDK12 | cyclin-dependent kinase 12 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDND1 | claudin domain containing 1 |
| COCH | cochlin |
| COL9A3 | collagen, type IX, alpha 3 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP13 | dual specificity phosphatase 13 |
| EED | embryonic ectoderm development |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXOC5 | exocyst complex component 5 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAS | Fas cell surface death receptor |
| FBLN1 | fibulin 1 |
| FRMD4B | FERM domain containing 4B |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| HABP4 | hyaluronan binding protein 4 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| ING4 | inhibitor of growth family, member 4 |
| IQCG | IQ motif containing G |
| ITGA10 | integrin, alpha 10 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC157562 | uncharacterized LOC157562 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MCL1 | myeloid cell leukemia 1 |
| MCOLN3 | mucolipin 3 |
| MED25 | mediator complex subunit 25 |
| MSH6 | mutS homolog 6 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NOL12 | nucleolar protein 12 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OLFML2A | olfactomedin-like 2A |
| OSMR | oncostatin M receptor |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| POPDC3 | popeye domain containing 3 |
| POU4F1 | POU class 4 homeobox 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCH | protein kinase C, eta |
| RAB5A | RAB5A, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RND2 | Rho family GTPase 2 |
| RUNX1 | runt-related transcription factor 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD5 | SMAD family member 5 |
| SNN | stannin |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SQLE | squalene epoxidase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX2 | syntaxin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNGR1 | synaptogyrin 1 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TOR1AIP1 | torsin A interacting protein 1 |
| TRIM2 | tripartite motif containing 2 |
| VLDLR | very low density lipoprotein receptor |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADRA2C | adrenoceptor alpha 2C |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARC | activity-regulated cytoskeleton-associated protein |
| B9D2 | B9 protein domain 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPN15 | calpain 15 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC94 | coiled-coil domain containing 94 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC20 | cell division cycle 20 |
| CENPE | centromere protein E, 312kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CIC | capicua transcriptional repressor |
| CLEC16A | C-type lectin domain family 16, member A |
| CNN2 | calponin 2 |
| CORT | cortistatin |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CTNNBL1 | catenin, beta like 1 |
| CUL9 | cullin 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYSF | dysferlin |
| ERI3 | ERI1 exoribonuclease family member 3 |
| FAM64A | family with sequence similarity 64, member A |
| FKBPL | FK506 binding protein like |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GALE | UDP-galactose-4-epimerase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH3 | G patch domain containing 3 |
| H1F0 | H1 histone family, member 0 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HJURP | Holliday junction recognition protein |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIF13A | kinesin family member 13A |
| KRT31 | keratin 31, type I |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MED9 | mediator complex subunit 9 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MITF | microphthalmia-associated transcription factor |
| MMP9 | matrix metallopeptidase 9 |
| MXD3 | MAX dimerization protein 3 |
| NEUROD4 | neuronal differentiation 4 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NLRX1 | NLR family member X1 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCDHB3 | protocadherin beta 3 |
| PLA2G3 | phospholipase A2, group III |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRR14L | proline rich 14-like |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RGS2 | regulator of G-protein signaling 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SMTN | smoothelin |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STEAP4 | STEAP family member 4 |
| SUSD6 | sushi domain containing 6 |
| TMEM121 | transmembrane protein 121 |
| TMEM39B | transmembrane protein 39B |
| TNRC6B | trinucleotide repeat containing 6B |
| TPCN1 | two pore segment channel 1 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TSGA10 | testis specific, 10 |
| TUBA3D | tubulin, alpha 3d |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF276 | zinc finger protein 276 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF804A | zinc finger protein 804A |
