| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pyrithyldione-2740 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ADRA1A | adrenoceptor alpha 1A |
| AQP1 | aquaporin 1 (Colton blood group) |
| ATXN3 | ataxin 3 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BMP8A | bone morphogenetic protein 8a |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C8A | complement component 8, alpha polypeptide |
| CALD1 | caldesmon 1 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCDC92 | coiled-coil domain containing 92 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CKM | creatine kinase, muscle |
| CLDN3 | claudin 3 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| EBF2 | early B-cell factor 2 |
| FAM13C | family with sequence similarity 13, member C |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FLJ11292 | |
| FOXA2 | forkhead box A2 |
| FOXL1 | forkhead box L1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GRK4 | G protein-coupled receptor kinase 4 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BN | histone cluster 1, H2bn |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXB3 | homeobox B3 |
| HPR | haptoglobin-related protein |
| IL1R1 | interleukin 1 receptor, type I |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL1RN | interleukin 1 receptor antagonist |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KLHL22 | kelch-like family member 22 |
| KRT81 | keratin 81, type II |
| KSR1 | kinase suppressor of ras 1 |
| LBX1 | ladybird homeobox 1 |
| LMF1 | lipase maturation factor 1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRAS | muscle RAS oncogene homolog |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MYO6 | myosin VI |
| NAG18 | NAG18 mRNA |
| NLGN1 | neuroligin 1 |
| NRG1 | neuregulin 1 |
| PADI4 | peptidyl arginine deiminase, type IV |
| PAX8 | paired box 8 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDX1 | pancreatic and duodenal homeobox 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PIP | prolactin-induced protein |
| PLCH1 | phospholipase C, eta 1 |
| PMP2 | peripheral myelin protein 2 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS6 | regulator of G-protein signaling 6 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SPAG8 | sperm associated antigen 8 |
| SPRR1A | small proline-rich protein 1A |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STATH | statherin |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TJP3 | tight junction protein 3 |
| TMEM212 | transmembrane protein 212 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| ZNF415 | zinc finger protein 415 |
| ZNF44 | zinc finger protein 44 |
| ZNF440 | zinc finger protein 440 |
| ZNF471 | zinc finger protein 471 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARG1 | arginase 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BOLA1 | bolA family member 1 |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC9 | coiled-coil domain containing 9 |
| CD300C | CD300c molecule |
| CD37 | CD37 molecule |
| CES3 | carboxylesterase 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN15 | claudin 15 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DENND5B | DENN/MADD domain containing 5B |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| EFNA4 | ephrin-A4 |
| EGR3 | early growth response 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| GID4 | GID complex subunit 4 |
| GK3P | glycerol kinase 3 pseudogene |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GRAMD1B | GRAM domain containing 1B |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2BH | histone cluster 1, H2bh |
| HOXC8 | homeobox C8 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEH1 | melanoma antigen family H1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NCS1 | neuronal calcium sensor 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OLAH | oleoyl-ACP hydrolase |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PADI2 | peptidyl arginine deiminase, type II |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| PORCN | porcupine homolog (Drosophila) |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RAB3A | RAB3A, member RAS oncogene family |
| RHBDD3 | rhomboid domain containing 3 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RNF122 | ring finger protein 122 |
| SCG5 | secretogranin V |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERINC5 | serine incorporator 5 |
| SGMS1 | sphingomyelin synthase 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPAG1 | sperm associated antigen 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STBD1 | starch binding domain 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM242 | transmembrane protein 242 |
| TMEM53 | transmembrane protein 53 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPM3 | tropomyosin 3 |
| TRIM25 | tripartite motif containing 25 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSC22D4 | TSC22 domain family, member 4 |
| UNC13B | unc-13 homolog B (C. elegans) |
| UPB1 | ureidopropionase, beta |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF155 | zinc finger protein 155 |
| ZNF16 | zinc finger protein 16 |
| ZNF177 | zinc finger protein 177 |
| ZNF215 | zinc finger protein 215 |
| ZNF225 | zinc finger protein 225 |
| ZNF34 | zinc finger protein 34 |
| ZNF492 | zinc finger protein 492 |
| ZNF528 | zinc finger protein 528 |