| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pyrithyldione-7153 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARMC9 | armadillo repeat containing 9 |
| ASF1A | anti-silencing function 1A histone chaperone |
| AURKA | aurora kinase A |
| BAG4 | BCL2-associated athanogene 4 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CABIN1 | calcineurin binding protein 1 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD22 | CD22 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CENPJ | centromere protein J |
| CNTNAP2 | contactin associated protein-like 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CTNNBL1 | catenin, beta like 1 |
| EEA1 | early endosome antigen 1 |
| ELL | elongation factor RNA polymerase II |
| EVI5 | ecotropic viral integration site 5 |
| FDX1 | ferredoxin 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GK | glycerol kinase |
| GLRX3 | glutaredoxin 3 |
| H2AFX | H2A histone family, member X |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HES2 | hes family bHLH transcription factor 2 |
| HLX | H2.0-like homeobox |
| HNF1B | HNF1 homeobox B |
| HOMER3 | homer scaffolding protein 3 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF5C | kinesin family member 5C |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LTC4S | leukotriene C4 synthase |
| MAPT | microtubule-associated protein tau |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MCL1 | myeloid cell leukemia 1 |
| MEGF9 | multiple EGF-like-domains 9 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MTAP | methylthioadenosine phosphorylase |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NF2 | neurofibromin 2 (merlin) |
| NLRX1 | NLR family member X1 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPR2 | natriuretic peptide receptor 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUFIP1 | nuclear fragile X mental retardation protein interacting protein 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PAX9 | paired box 9 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCM1 | pericentriolar material 1 |
| PKP3 | plakophilin 3 |
| PLK4 | polo-like kinase 4 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRMT2IP | PRMT2 interacting protein |
| RAB28 | RAB28, member RAS oncogene family |
| RGS14 | regulator of G-protein signaling 14 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SERINC5 | serine incorporator 5 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STK3 | serine/threonine kinase 3 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D30 | TBC1 domain family, member 30 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM63A | transmembrane protein 63A |
| TMEM80 | transmembrane protein 80 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIM25 | tripartite motif containing 25 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBG2 | tubulin, gamma 2 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| VCAN | versican |
| VWA8 | von Willebrand factor A domain containing 8 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADAMTSL3 | ADAMTS-like 3 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC69 | coiled-coil domain containing 69 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CFAP44 | cilia and flagella associated protein 44 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLK1 | CDC-like kinase 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| E2F1 | E2F transcription factor 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| EPPK1 | epiplakin 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| F8 | coagulation factor VIII, procoagulant component |
| FANCC | Fanconi anemia, complementation group C |
| FOXC1 | forkhead box C1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIRA | histone cell cycle regulator |
| HOXC10 | homeobox C10 |
| IFI44L | interferon-induced protein 44-like |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL17RA | interleukin 17 receptor A |
| IPO8 | importin 8 |
| IQCG | IQ motif containing G |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0355 | KIAA0355 |
| KIAA0922 | KIAA0922 |
| KPTN | kaptin (actin binding protein) |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAMLD1 | mastermind-like domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTD1 | mbt domain containing 1 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| METTL16 | methyltransferase like 16 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MXD3 | MAX dimerization protein 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALB2 | partner and localizer of BRCA2 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PLAC8 | placenta-specific 8 |
| PLCD1 | phospholipase C, delta 1 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| POLM | polymerase (DNA directed), mu |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRMT7 | protein arginine methyltransferase 7 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| ROGDI | rogdi homolog (Drosophila) |
| SCAI | suppressor of cancer cell invasion |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SESN1 | sestrin 1 |
| SETD1B | SET domain containing 1B |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SMA4 | glucuronidase, beta pseudogene |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPIDR | scaffolding protein involved in DNA repair |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STBD1 | starch binding domain 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TDRD3 | tudor domain containing 3 |
| TEX40 | testis expressed 40 |
| THOC6 | THO complex 6 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM242 | transmembrane protein 242 |
| WDR25 | WD repeat domain 25 |
| WDR37 | WD repeat domain 37 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF112 | zinc finger protein 112 |
| ZNF16 | zinc finger protein 16 |
| ZNF34 | zinc finger protein 34 |
| ZNF385D | zinc finger protein 385D |
| ZNF552 | zinc finger protein 552 |
| ZNF574 | zinc finger protein 574 |
| ZNF84 | zinc finger protein 84 |
| ZXDC | ZXD family zinc finger C |
