pyrophosphatase activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. (Gene Ontology, GO_0016462)
External Link http://amigo.geneontology.org/amigo/term/GO:0016462
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Genes

60 genes performing the pyrophosphatase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACYP1 acylphosphatase 1, erythrocyte (common) type
ACYP2 acylphosphatase 2, muscle type
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALPL alkaline phosphatase, liver/bone/kidney
ASMTL acetylserotonin O-methyltransferase-like
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CILP2 cartilage intermediate layer protein 2
DCP2 decapping mRNA 2
DCPS decapping enzyme, scavenger
DCTPP1 dCTP pyrophosphatase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DOLPP1 dolichyldiphosphatase 1
DXO decapping exoribonuclease
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8
FHIT fragile histidine triad
FITM2 fat storage-inducing transmembrane protein 2
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
NTPCR nucleoside-triphosphatase, cancer-related
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUDT4B nudix hydrolase 4B
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PHOSPHO1 phosphatase, orphan 1
PLPP1 phospholipid phosphatase 1
PLPP4 phospholipid phosphatase 4
PLPP5 phospholipid phosphatase 5
PLPP6 phospholipid phosphatase 6
PPA1 pyrophosphatase (inorganic) 1
PPA2 pyrophosphatase (inorganic) 2
PRUNE1 prune exopolyphosphatase 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
THTPA thiamine triphosphatase
TRPM2 transient receptor potential cation channel, subfamily M, member 2