| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pyrvinium-2957 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACOT11 | acyl-CoA thioesterase 11 |
| AREG | amphiregulin |
| ARL4C | ADP-ribosylation factor-like 4C |
| AURKA | aurora kinase A |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BDNF | brain-derived neurotrophic factor |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG2 | BTG family, member 2 |
| C5AR1 | complement component 5a receptor 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD70 | CD70 molecule |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CEP72 | centrosomal protein 72kDa |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNTN1 | contactin 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CREM | cAMP responsive element modulator |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| EPHB6 | EPH receptor B6 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FCMR | Fc fragment of IgM receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| FRY | furry homolog (Drosophila) |
| FTH1 | ferritin, heavy polypeptide 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GPR183 | G protein-coupled receptor 183 |
| GRAMD3 | GRAM domain containing 3 |
| HBEGF | heparin-binding EGF-like growth factor |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4E | histone cluster 1, H4e |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA5 | homeobox A5 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IL23A | interleukin 23, alpha subunit p19 |
| IL24 | interleukin 24 |
| INHBA | inhibin, beta A |
| JAG1 | jagged 1 |
| JUNB | jun B proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MT2A | metallothionein 2A |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OSM | oncostatin M |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PLAUR | plasminogen activator, urokinase receptor |
| PRDM1 | PR domain containing 1, with ZNF domain |
| QPRT | quinolinate phosphoribosyltransferase |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHOB | ras homolog family member B |
| RHOD | ras homolog family member D |
| RND1 | Rho family GTPase 1 |
| RTCA | RNA 3'-terminal phosphate cyclase |
| RUFY3 | RUN and FYVE domain containing 3 |
| RXRA | retinoid X receptor, alpha |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SH2D2A | SH2 domain containing 2A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIK1 | salt-inducible kinase 1 |
| SKIL | SKI-like proto-oncogene |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 |
| SOCS3 | suppressor of cytokine signaling 3 |
| STON1 | stonin 1 |
| STX11 | syntaxin 11 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TARP | TCR gamma alternate reading frame protein |
| THBS1 | thrombospondin 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TYMP | thymidine phosphorylase |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ADORA2B | adenosine A2b receptor |
| ADRB2 | adrenoceptor beta 2, surface |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| C21ORF59 | chromosome 21 open reading frame 59 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CCDC51 | coiled-coil domain containing 51 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CHMP7 | charged multivesicular body protein 7 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CYBRD1 | cytochrome b reductase 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM57A | family with sequence similarity 57, member A |
| FASTKD5 | FAST kinase domains 5 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GIMAP6 | GTPase, IMAP family member 6 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HELLS | helicase, lymphoid-specific |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HSPA4L | heat shock 70kDa protein 4-like |
| INSIG2 | insulin induced gene 2 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLHL26 | kelch-like family member 26 |
| LINS | lines homolog (Drosophila) |
| LRRC42 | leucine rich repeat containing 42 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| METTL8 | methyltransferase like 8 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MOSPD3 | motile sperm domain containing 3 |
| MSRB1 | methionine sulfoxide reductase B1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NDRG1 | N-myc downstream regulated 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFE2 | nuclear factor, erythroid 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PNOC | prepronociceptin |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRDM13 | PR domain containing 13 |
| PTGES2 | prostaglandin E synthase 2 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RFXAP | regulatory factor X-associated protein |
| RGS13 | regulator of G-protein signaling 13 |
| RLF | rearranged L-myc fusion |
| RRAGA | Ras-related GTP binding A |
| SALL2 | spalt-like transcription factor 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SPP1 | secreted phosphoprotein 1 |
| STBD1 | starch binding domain 1 |
| TCTN1 | tectonic family member 1 |
| TMEM45A | transmembrane protein 45A |
| TSFM | Ts translation elongation factor, mitochondrial |
| TUBB6 | tubulin, beta 6 class V |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UNG | uracil-DNA glycosylase |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VGLL4 | vestigial-like family member 4 |
| WDR3 | WD repeat domain 3 |
| WT1-AS | WT1 antisense RNA |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF395 | zinc finger protein 395 |
| ZNF574 | zinc finger protein 574 |
| ZNF654 | zinc finger protein 654 |
