| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pyrvinium-3518 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AHR | aryl hydrocarbon receptor |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| B9D1 | B9 protein domain 1 |
| BCAP29 | B-cell receptor-associated protein 29 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BLNK | B-cell linker |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTG2 | BTG family, member 2 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEL | carboxyl ester lipase |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCA2 | chloride channel accessory 2 |
| CLDN1 | claudin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHA2 | EPH receptor A2 |
| ETV5 | ets variant 5 |
| FAM212B | family with sequence similarity 212, member B |
| FAM46A | family with sequence similarity 46, member A |
| FAS | Fas cell surface death receptor |
| FKRP | fukutin related protein |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOSL1 | FOS-like antigen 1 |
| FOXN3 | forkhead box N3 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLS | glutaminase |
| GPR87 | G protein-coupled receptor 87 |
| GRB10 | growth factor receptor-bound protein 10 |
| GTPBP2 | GTP binding protein 2 |
| HDAC5 | histone deacetylase 5 |
| HOXA9 | homeobox A9 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| IRF4 | interferon regulatory factor 4 |
| IRS2 | insulin receptor substrate 2 |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| LIF | leukemia inhibitory factor |
| LOC157562 | uncharacterized LOC157562 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARS | methionyl-tRNA synthetase |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MST1 | macrophage stimulating 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NHLH2 | nescient helix loop helix 2 |
| NMT2 | N-myristoyltransferase 2 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PER1 | period circadian clock 1 |
| PLAU | plasminogen activator, urokinase |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS20 | regulator of G-protein signaling 20 |
| RNF19B | ring finger protein 19B |
| SAV1 | salvador family WW domain containing protein 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SESN1 | sestrin 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STOM | stomatin |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TES | testin LIM domain protein |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TLR2 | toll-like receptor 2 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TP53TG1 | TP53 target 1 (non-protein coding) |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIB3 | tribbles pseudokinase 3 |
| USP2 | ubiquitin specific peptidase 2 |
| VEGFA | vascular endothelial growth factor A |
| XPC | xeroderma pigmentosum, complementation group C |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMC6 | armadillo repeat containing 6 |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CBR3 | carbonyl reductase 3 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CCNO | cyclin O |
| CDCA8 | cell division cycle associated 8 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CENPQ | centromere protein Q |
| CEP97 | centrosomal protein 97kDa |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EAF2 | ELL associated factor 2 |
| EFHD2 | EF-hand domain family, member D2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| FAM155B | family with sequence similarity 155, member B |
| FAM57A | family with sequence similarity 57, member A |
| FBXO5 | F-box protein 5 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GALK1 | galactokinase 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPR19 | G protein-coupled receptor 19 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IRX5 | iroquois homeobox 5 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0125 | KIAA0125 |
| KIF11 | kinesin family member 11 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC20 | leucine rich repeat containing 20 |
| MCM10 | minichromosome maintenance complex component 10 |
| MEIS1 | Meis homeobox 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYL5 | myosin, light chain 5, regulatory |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| ORC1 | origin recognition complex, subunit 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| POLQ | polymerase (DNA directed), theta |
| PPIF | peptidylprolyl isomerase F |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR15L | proline rich 15-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAOK1 | TAO kinase 1 |
| TARP | TCR gamma alternate reading frame protein |
| TMEM164 | transmembrane protein 164 |
| TMEM180 | transmembrane protein 180 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRIM45 | tripartite motif containing 45 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF408 | zinc finger protein 408 |
| ZNF696 | zinc finger protein 696 |
| ZXDC | ZXD family zinc finger C |
