| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pyrvinium-5439 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANXA1 | annexin A1 |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BBC3 | BCL2 binding component 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BLNK | B-cell linker |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CEL | carboxyl ester lipase |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN1 | claudin 1 |
| CREM | cAMP responsive element modulator |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIO2 | deiodinase, iodothyronine, type II |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHA2 | EPH receptor A2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV5 | ets variant 5 |
| FAM46A | family with sequence similarity 46, member A |
| FAS | Fas cell surface death receptor |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GLS | glutaminase |
| GPR87 | G protein-coupled receptor 87 |
| GRB10 | growth factor receptor-bound protein 10 |
| GTPBP2 | GTP binding protein 2 |
| HDAC5 | histone deacetylase 5 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| JUND | jun D proto-oncogene |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LDB3 | LIM domain binding 3 |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARS | methionyl-tRNA synthetase |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MT1F | metallothionein 1F |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAV2 | neuron navigator 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NHLH2 | nescient helix loop helix 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIDD1 | p53-induced death domain protein 1 |
| PLAU | plasminogen activator, urokinase |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB32 | RAB32, member RAS oncogene family |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RGS20 | regulator of G-protein signaling 20 |
| RNF19B | ring finger protein 19B |
| S100P | S100 calcium binding protein P |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIRT5 | sirtuin 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAI2 | snail family zinc finger 2 |
| STOM | stomatin |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TES | testin LIM domain protein |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TSC22D3 | TSC22 domain family, member 3 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| XPC | xeroderma pigmentosum, complementation group C |
| ZNF384 | zinc finger protein 384 |
| ZNF549 | zinc finger protein 549 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AIM1 | absent in melanoma 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARMC6 | armadillo repeat containing 6 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BLM | Bloom syndrome, RecQ helicase-like |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CBX8 | chromobox homolog 8 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CCNF | cyclin F |
| CCNO | cyclin O |
| CDCA3 | cell division cycle associated 3 |
| CDCA8 | cell division cycle associated 8 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CENPE | centromere protein E, 312kDa |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| E2F8 | E2F transcription factor 8 |
| EFHD2 | EF-hand domain family, member D2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| FAAH | fatty acid amide hydrolase |
| FAM64A | family with sequence similarity 64, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO5 | F-box protein 5 |
| FHOD1 | formin homology 2 domain containing 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| GHR | growth hormone receptor |
| GPR19 | G protein-coupled receptor 19 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HIST1H4D | histone cluster 1, H4d |
| HPN | hepsin |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| IFT140 | intraflagellar transport 140 |
| IL17RA | interleukin 17 receptor A |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRX5 | iroquois homeobox 5 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF18A | kinesin family member 18A |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| LHX6 | LIM homeobox 6 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC61 | leucine rich repeat containing 61 |
| MCM10 | minichromosome maintenance complex component 10 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MXD3 | MAX dimerization protein 3 |
| NDC80 | NDC80 kinetochore complex component |
| NEK11 | NIMA-related kinase 11 |
| NES | nestin |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| ORC1 | origin recognition complex, subunit 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLK1 | polo-like kinase 1 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR15L | proline rich 15-like |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PVRL3 | poliovirus receptor-related 3 |
| RBL1 | retinoblastoma-like 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| SKI | SKI proto-oncogene |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TIPIN | TIMELESS interacting protein |
| TMEM180 | transmembrane protein 180 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TROAP | trophinin associated protein |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASH2 | vasohibin 2 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
