| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the pyrvinium-870 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AMOTL2 | angiomotin like 2 |
| APOE | apolipoprotein E |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARMC6 | armadillo repeat containing 6 |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTG2 | BTG family, member 2 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLGN | calmegin |
| CLU | clusterin |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EPHA2 | EPH receptor A2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAS | Fas cell surface death receptor |
| FBXO2 | F-box protein 2 |
| FOSL1 | FOS-like antigen 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GATA6 | GATA binding protein 6 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GK | glycerol kinase |
| GPR135 | G protein-coupled receptor 135 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GPR87 | G protein-coupled receptor 87 |
| GRB10 | growth factor receptor-bound protein 10 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK2 | glutamate receptor, ionotropic, kainate 2 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GTPBP2 | GTP binding protein 2 |
| HIC2 | hypermethylated in cancer 2 |
| IL6ST | interleukin 6 signal transducer |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| JUND | jun D proto-oncogene |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KIF21B | kinesin family member 21B |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLHL24 | kelch-like family member 24 |
| LAMA4 | laminin, alpha 4 |
| LOC100129648 | uncharacterized LOC100129648 |
| LPIN1 | lipin 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1B | microtubule-associated protein 1B |
| MARS | methionyl-tRNA synthetase |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMP1 | matrix metallopeptidase 1 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MT1E | metallothionein 1E |
| MYCNOS | MYCN opposite strand |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| NF1 | neurofibromin 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKTR | natural killer cell triggering receptor |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PAPOLG | poly(A) polymerase gamma |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PSPH | phosphoserine phosphatase |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| SESN1 | sestrin 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAI2 | snail family zinc finger 2 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| TES | testin LIM domain protein |
| TGFA | transforming growth factor, alpha |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM36 | tripartite motif containing 36 |
| TSC22D3 | TSC22 domain family, member 3 |
| USP2 | ubiquitin specific peptidase 2 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF639 | zinc finger protein 639 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACO1 | aconitase 1, soluble |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKRD36B | ankyrin repeat domain 36B |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ATG2A | autophagy related 2A |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BARD1 | BRCA1 associated RING domain 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCNE2 | cyclin E2 |
| CEP170B | centrosomal protein 170B |
| CHMP6 | charged multivesicular body protein 6 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EDC4 | enhancer of mRNA decapping 4 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENDOD1 | endonuclease domain containing 1 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERCC5 | excision repair cross-complementation group 5 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FANCG | Fanconi anemia, complementation group G |
| FRG1 | FSHD region gene 1 |
| GHR | growth hormone receptor |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate |
| HHEX | hematopoietically expressed homeobox |
| HIST1H2AM | histone cluster 1, H2am |
| HSPA2 | heat shock 70kDa protein 2 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KLC2 | kinesin light chain 2 |
| KRT15 | keratin 15, type I |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LOC100272216 | uncharacterized LOC100272216 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LYRM2 | LYR motif containing 2 |
| MANBA | mannosidase, beta A, lysosomal |
| MCM10 | minichromosome maintenance complex component 10 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NABP2 | nucleic acid binding protein 2 |
| NBEAL2 | neurobeachin-like 2 |
| NCOA4 | nuclear receptor coactivator 4 |
| NES | nestin |
| NKRF | NFKB repressing factor |
| NLK | nemo-like kinase |
| NRD1 | nardilysin (N-arginine dibasic convertase) |
| OTUD3 | OTU deubiquitinase 3 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLA2G15 | phospholipase A2, group XV |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PRR15L | proline rich 15-like |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| REPIN1 | replication initiator 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SELENBP1 | selenium binding protein 1 |
| SH2B2 | SH2B adaptor protein 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SIRT7 | sirtuin 7 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TESK2 | testis-specific kinase 2 |
| TH | tyrosine hydroxylase |
| TMEM11 | transmembrane protein 11 |
| TNS2 | tensin 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF107 | zinc finger protein 107 |
| ZNF248 | zinc finger protein 248 |
| ZNF394 | zinc finger protein 394 |
| ZNF408 | zinc finger protein 408 |
| ZNF778 | zinc finger protein 778 |
| ZXDC | ZXD family zinc finger C |
