| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pyrvinium-978 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADM | adrenomedullin |
| AKR1D1 | aldo-keto reductase family 1, member D1 |
| AMOTL2 | angiomotin like 2 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANXA1 | annexin A1 |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATF3 | activating transcription factor 3 |
| BBC3 | BCL2 binding component 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTG2 | BTG family, member 2 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDK12 | cyclin-dependent kinase 12 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CTTN | cortactin |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIAPH1 | diaphanous-related formin 1 |
| DMPK | dystrophia myotonica-protein kinase |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV5 | ets variant 5 |
| FAS | Fas cell surface death receptor |
| FBLN1 | fibulin 1 |
| FOSL1 | FOS-like antigen 1 |
| FOXO1 | forkhead box O1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GPR87 | G protein-coupled receptor 87 |
| GRB10 | growth factor receptor-bound protein 10 |
| GTPBP2 | GTP binding protein 2 |
| HDAC11 | histone deacetylase 11 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL17RA | interleukin 17 receptor A |
| INHBE | inhibin, beta E |
| JUND | jun D proto-oncogene |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| LPXN | leupaxin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1B | microtubule-associated protein 1B |
| MAP1S | microtubule-associated protein 1S |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMRN2 | multimerin 2 |
| MTRF1L | mitochondrial translational release factor 1-like |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NOTCH1 | notch 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPTN | optineurin |
| PCDH1 | protocadherin 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAU | plasminogen activator, urokinase |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RAB32 | RAB32, member RAS oncogene family |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RNF19B | ring finger protein 19B |
| RPL5 | ribosomal protein L5 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SESN1 | sestrin 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMAD3 | SMAD family member 3 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TES | testin LIM domain protein |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TGFB2 | transforming growth factor, beta 2 |
| TLR2 | toll-like receptor 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| ZNF205 | zinc finger protein 205 |
| ZNF580 | zinc finger protein 580 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ABHD10 | abhydrolase domain containing 10 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASF1B | anti-silencing function 1B histone chaperone |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B3GNT1 | |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA2 | carbonic anhydrase II |
| CCDC15 | coiled-coil domain containing 15 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CDC6 | cell division cycle 6 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CNPY3 | canopy FGF signaling regulator 3 |
| COL4A5 | collagen, type IV, alpha 5 |
| CTSV | cathepsin V |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DENND1B | DENN/MADD domain containing 1B |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFHD2 | EF-hand domain family, member D2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM50B | family with sequence similarity 50, member B |
| FAM63A | family with sequence similarity 63, member A |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPR19 | G protein-coupled receptor 19 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H3G | histone cluster 1, H3g |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IGFLR1 | IGF-like family receptor 1 |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IPP | intracisternal A particle-promoted polypeptide |
| KIFC1 | kinesin family member C1 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMNB1 | lamin B1 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
| MAGEH1 | melanoma antigen family H1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) |
| METTL2B | methyltransferase like 2B |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL17 | mitochondrial ribosomal protein L17 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NBEAL2 | neurobeachin-like 2 |
| NCS1 | neuronal calcium sensor 1 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| ORC1 | origin recognition complex, subunit 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PMP22 | peripheral myelin protein 22 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRR15L | proline rich 15-like |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB8B | RAB8B, member RAS oncogene family |
| RAD51AP1 | RAD51 associated protein 1 |
| RANBP6 | RAN binding protein 6 |
| RARS | arginyl-tRNA synthetase |
| RPA2 | replication protein A2, 32kDa |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBCC | tubulin folding cofactor C |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAM2 | translocation associated membrane protein 2 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| ZNF778 | zinc finger protein 778 |
| ZNF813 | zinc finger protein 813 |
