pyrvinium Gene Set
Genes
29 genes differentially expressed following the pyrvinium small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KLHDC2
|
kelch domain containing 2
|
3.97036
|
|
CDKN1A
|
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
|
3.20328
|
|
SIK1
|
salt-inducible kinase 1
|
3.14806
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLK1
|
polo-like kinase 1
|
-5.50299
|
|
HJURP
|
Holliday junction recognition protein
|
-4.04214
|
|
TDP1
|
tyrosyl-DNA phosphodiesterase 1
|
-3.91681
|
|
KIF20B
|
kinesin family member 20B
|
-3.76655
|
|
NCAPH
|
non-SMC condensin I complex, subunit H
|
-3.53776
|
|
SPC25
|
SPC25, NDC80 kinetochore complex component
|
-3.45375
|
|
CDCA3
|
cell division cycle associated 3
|
-3.43654
|
|
TK1
|
thymidine kinase 1, soluble
|
-3.38091
|
|
CENPI
|
centromere protein I
|
-3.36564
|
|
KIF23
|
kinesin family member 23
|
-3.35836
|
|
BUB1
|
BUB1 mitotic checkpoint serine/threonine kinase
|
-3.35559
|
|
WDHD1
|
WD repeat and HMG-box DNA binding protein 1
|
-3.32701
|
|
GINS2
|
GINS complex subunit 2 (Psf2 homolog)
|
-3.30652
|
|
PRC1
|
protein regulator of cytokinesis 1
|
-3.29423
|
|
PRIM2
|
primase, DNA, polypeptide 2 (58kDa)
|
-3.24361
|
|
PIMREG
|
PICALM interacting mitotic regulator
|
-3.20256
|
|
MCM10
|
minichromosome maintenance complex component 10
|
-3.18124
|
|
GTSE1
|
G-2 and S-phase expressed 1
|
-3.17577
|
|
POP1
|
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
|
-3.163
|
|
KIF15
|
kinesin family member 15
|
-3.12189
|
|
KIF20A
|
kinesin family member 20A
|
-3.10514
|
|
TROAP
|
trophinin associated protein
|
-3.08572
|
|
UBQLN2
|
ubiquilin 2
|
-3.08307
|
|
MKI67
|
marker of proliferation Ki-67
|
-3.04951
|
|
CENPA
|
centromere protein A
|
-3.02262
|
|
CEP55
|
centrosomal protein 55kDa
|
-3.012
|
