quercetin-2859 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the quercetin-2859 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALPK1 alpha-kinase 1
ATF3 activating transcription factor 3
CD82 CD82 molecule
CDK12 cyclin-dependent kinase 12
CDKL3 cyclin-dependent kinase-like 3
CFLAR CASP8 and FADD-like apoptosis regulator
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
ECE1 endothelin converting enzyme 1
EDRF1 erythroid differentiation regulatory factor 1
EGR1 early growth response 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ERBB2 erb-b2 receptor tyrosine kinase 2
ETV6 ets variant 6
FAS Fas cell surface death receptor
FBXO11 F-box protein 11
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GSK3A glycogen synthase kinase 3 alpha
GTPBP4 GTP binding protein 4
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HMOX1 heme oxygenase 1
HPX hemopexin
HSDL2 hydroxysteroid dehydrogenase like 2
IL5RA interleukin 5 receptor, alpha
ING4 inhibitor of growth family, member 4
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
KIAA0368 KIAA0368
KIF21B kinesin family member 21B
KLHL24 kelch-like family member 24
LOC157562 uncharacterized LOC157562
LRRC17 leucine rich repeat containing 17
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAT2A methionine adenosyltransferase II, alpha
MED18 mediator complex subunit 18
MIA3 melanoma inhibitory activity family, member 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NIPAL3 NIPA-like domain containing 3
NUP88 nucleoporin 88kDa
ORAI2 ORAI calcium release-activated calcium modulator 2
OSGIN1 oxidative stress induced growth inhibitor 1
OVOL2 ovo-like zinc finger 2
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PVR poliovirus receptor
RAB11B RAB11B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF122 ring finger protein 122
RNFT1 ring finger protein, transmembrane 1
RPL31 ribosomal protein L31
RSU1 Ras suppressor protein 1
SAMD4A sterile alpha motif domain containing 4A
SBNO1 strawberry notch homolog 1 (Drosophila)
SETD4 SET domain containing 4
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35F5 solute carrier family 35, member F5
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRSF5 serine/arginine-rich splicing factor 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TDRKH tudor and KH domain containing
TEP1 telomerase-associated protein 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPMT thiopurine S-methyltransferase
TRIM16 tripartite motif containing 16
UBE3A ubiquitin protein ligase E3A
UBQLN4 ubiquilin 4
UCN urocortin
USP22 ubiquitin specific peptidase 22
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VEGFA vascular endothelial growth factor A
ZC3H13 zinc finger CCCH-type containing 13
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF202 zinc finger protein 202
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
AGO3 argonaute RISC catalytic component 3
BAGE B melanoma antigen
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBS7 Bardet-Biedl syndrome 7
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C12ORF4 chromosome 12 open reading frame 4
C1ORF112 chromosome 1 open reading frame 112
C5AR2 complement component 5a receptor 2
CCNH cyclin H
CCNO cyclin O
CDC27 cell division cycle 27
CDC7 cell division cycle 7
CENPE centromere protein E, 312kDa
CEP76 centrosomal protein 76kDa
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DENND4C DENN/MADD domain containing 4C
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMXL1 Dmx-like 1
DTWD1 DTW domain containing 1
EAF2 ELL associated factor 2
EFNA1 ephrin-A1
ELP3 elongator acetyltransferase complex subunit 3
ERBB2IP erbb2 interacting protein
EXOC5 exocyst complex component 5
FAM169A family with sequence similarity 169, member A
FAM208A family with sequence similarity 208, member A
FAM46C family with sequence similarity 46, member C
FBXW12 F-box and WD repeat domain containing 12
FNBP1L formin binding protein 1-like
GBP2 guanylate binding protein 2, interferon-inducible
GHR growth hormone receptor
GK3P glycerol kinase 3 pseudogene
HCFC2 host cell factor C2
HELZ helicase with zinc finger
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA4L heat shock 70kDa protein 4-like
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI35 interferon-induced protein 35
IFT81 intraflagellar transport 81
IFT88 intraflagellar transport 88
INTS8 integrator complex subunit 8
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KDM5C lysine (K)-specific demethylase 5C
KIF18A kinesin family member 18A
KIF20B kinesin family member 20B
KLF3 Kruppel-like factor 3 (basic)
KLHL2 kelch-like family member 2
KRIT1 KRIT1, ankyrin repeat containing
LIMA1 LIM domain and actin binding 1
LINC00115 long intergenic non-protein coding RNA 115
LRRC20 leucine rich repeat containing 20
LTN1 listerin E3 ubiquitin protein ligase 1
LYPD1 LY6/PLAUR domain containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MFN1 mitofusin 1
MSH2 mutS homolog 2
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYL5 myosin, light chain 5, regulatory
NBEA neurobeachin
NCAPG non-SMC condensin I complex, subunit G
OCLN occludin
ORC2 origin recognition complex, subunit 2
OSTM1 osteopetrosis associated transmembrane protein 1
PCNXL4 pecanex-like 4 (Drosophila)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHTF1 putative homeodomain transcription factor 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
RINT1 RAD50 interactor 1
RPAP3 RNA polymerase II associated protein 3
SCN1B sodium channel, voltage gated, type I beta subunit
SFXN1 sideroflexin 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPAG1 sperm associated antigen 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SSFA2 sperm specific antigen 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TARP TCR gamma alternate reading frame protein
TDRD7 tudor domain containing 7
TRABD TraB domain containing
TRMT61B tRNA methyltransferase 61B
TTC33 tetratricopeptide repeat domain 33
UNC50 unc-50 homolog (C. elegans)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VRK1 vaccinia related kinase 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC13 zinc finger, DHHC-type containing 13
ZFYVE16 zinc finger, FYVE domain containing 16