quercetin-4264 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the quercetin-4264 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOXL acyl-CoA oxidase-like
ANGPT2 angiopoietin 2
ARHGAP25 Rho GTPase activating protein 25
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ATP10A ATPase, class V, type 10A
BATF basic leucine zipper transcription factor, ATF-like
BPY2 basic charge, Y-linked, 2
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CDHR5 cadherin-related family member 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
COL14A1 collagen, type XIV, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRH corticotropin releasing hormone
CSHL1 chorionic somatomammotropin hormone-like 1
CYSLTR1 cysteinyl leukotriene receptor 1
DDN dendrin
DENND1C DENN/MADD domain containing 1C
EBF2 early B-cell factor 2
ELN elastin
FGF6 fibroblast growth factor 6
FGFR2 fibroblast growth factor receptor 2
GRM8 glutamate receptor, metabotropic 8
GUCA2A guanylate cyclase activator 2A (guanylin)
GZMK granzyme K (granzyme 3; tryptase II)
HNMT histamine N-methyltransferase
HPSE2 heparanase 2 (inactive)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICA1 islet cell autoantigen 1, 69kDa
ICOSLG inducible T-cell co-stimulator ligand
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INHBA inhibin, beta A
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KERA keratocan
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0125 KIAA0125
KIF1C kinesin family member 1C
KLHDC8A kelch domain containing 8A
KRT14 keratin 14, type I
KRTAP5-9 keratin associated protein 5-9
LAMB4 laminin, beta 4
LDB3 LIM domain binding 3
LRTM1 leucine-rich repeats and transmembrane domains 1
LYZ lysozyme
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MED16 mediator complex subunit 16
MNMIP1 manchette microtubule inner protein 1
NAG18 NAG18 mRNA
NEK9 NIMA-related kinase 9
NFIB nuclear factor I/B
NPR1 natriuretic peptide receptor 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRAP nebulin-related anchoring protein
NRG1 neuregulin 1
PADI4 peptidyl arginine deiminase, type IV
PCDHGB6 protocadherin gamma subfamily B, 6
PKD2L2 polycystic kidney disease 2-like 2
PLVAP plasmalemma vesicle associated protein
PLXDC1 plexin domain containing 1
PRDM9 PR domain containing 9
PTEN phosphatase and tensin homolog
RAB11B RAB11B, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGS12 regulator of G-protein signaling 12
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
SCN2B sodium channel, voltage gated, type II beta subunit
SLC6A16 solute carrier family 6, member 16
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMC1A structural maintenance of chromosomes 1A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX5 SRY (sex determining region Y)-box 5
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPRR2B small proline-rich protein 2B
SRPK3 SRSF protein kinase 3
SSX1 synovial sarcoma, X breakpoint 1
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
SULF1 sulfatase 1
SYK spleen tyrosine kinase
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THPO thrombopoietin
TLK1 tousled-like kinase 1
TMEM212 transmembrane protein 212
TP53I11 tumor protein p53 inducible protein 11
TP73-AS1 TP73 antisense RNA 1
TRO trophinin
VNN1 vanin 1
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XYLB xylulokinase homolog (H. influenzae)
ZC3H13 zinc finger CCCH-type containing 13
ZMYND8 zinc finger, MYND-type containing 8
ZNF484 zinc finger protein 484

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AGO4 argonaute RISC catalytic component 4
AIM2 absent in melanoma 2
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBC3 BCL2 binding component 3
C22ORF46 chromosome 22 open reading frame 46
CADPS2 Ca++-dependent secretion activator 2
CFAP69 cilia and flagella associated protein 69
CHRDL1 chordin-like 1
CLDN14 claudin 14
CNPY4 canopy FGF signaling regulator 4
CRMP1 collapsin response mediator protein 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
CYBRD1 cytochrome b reductase 1
CYTH3 cytohesin 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DMBT1 deleted in malignant brain tumors 1
DOLK dolichol kinase
EFNA3 ephrin-A3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
ELSPBP1 epididymal sperm binding protein 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERF Ets2 repressor factor
EXD3 exonuclease 3'-5' domain containing 3
FAM69A family with sequence similarity 69, member A
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GLI3 GLI family zinc finger 3
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIST1H2AK histone cluster 1, H2ak
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HMHA1 histocompatibility (minor) HA-1
HOXA1 homeobox A1
HOXB2 homeobox B2
HOXC5 homeobox C5
HSF2BP heat shock transcription factor 2 binding protein
IL17RA interleukin 17 receptor A
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK4 interleukin-1 receptor-associated kinase 4
ITPKA inositol-trisphosphate 3-kinase A
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIF13A kinesin family member 13A
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LENEP lens epithelial protein
LINC00260 long intergenic non-protein coding RNA 260
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MUC3A mucin 3A, cell surface associated
MYO1E myosin IE
NDE1 nudE neurodevelopment protein 1
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAIP2B poly(A) binding protein interacting protein 2B
PALMD palmdelphin
PCDHGB5 protocadherin gamma subfamily B, 5
PDE8B phosphodiesterase 8B
PGM5 phosphoglucomutase 5
PHEX phosphate regulating endopeptidase homolog, X-linked
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RNF122 ring finger protein 122
RPH3AL rabphilin 3A-like (without C2 domains)
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SLC16A4 solute carrier family 16, member 4
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYCP2 synaptonemal complex protein 2
TAOK3 TAO kinase 3
TESK2 testis-specific kinase 2
TEX40 testis expressed 40
THRAP3 thyroid hormone receptor associated protein 3
TMEM40 transmembrane protein 40
TONSL tonsoku-like, DNA repair protein
TRIM25 tripartite motif containing 25
TSPAN8 tetraspanin 8
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
ZFP30 ZFP30 zinc finger protein
ZNF33B zinc finger protein 33B
ZNF41 zinc finger protein 41
ZNF492 zinc finger protein 492
ZNF552 zinc finger protein 552